Showing metabocard for Beauvericin (MMDBc0002677)
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2021-05-14 20:56:22 UTC | ||||||||||||
| Update Date | 2025-10-07 16:04:37 UTC | ||||||||||||
| Metabolite ID | MMDBc0002677 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Beauvericin | ||||||||||||
| Description | Beauvericin is a mycotoxin belonging to the class of secondary metabolites produced primarily by fungi of the genus Fusarium, as well as by entomopathogenic fungi such as Beauveria bassiana and Isaria fumosorosea. This compound has garnered attention due to its frequent detection in food and feed, raising significant concerns regarding its toxicological risks for human and animal health, a concept encapsulated in the One Health approach (PMID:41005507 ). Experimental studies have highlighted its toxic effects, including disruptions in cell cycle progression, such as the G2/M transition during mouse oocyte maturation (PMID:40840853 ). Additionally, beauvericin has been linked to reductions in Fusarium biomass and associated mycotoxins, indicating its potential role in the ecological dynamics of fungal contamination (PMID:40999249 ). Its insecticidal properties have also been explored, suggesting potential applications as a natural pesticide against agricultural pests like Leptinotarsa decemlineata (PMID:40937573 ). Overall, beauvericin represents a complex interplay of chemical properties and biological impacts, underscoring the need for further research into its safety and environmental implications (PMID:41005507 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C45H57N3O9 | ||||||||||||
| Average Mass | 783.963 | ||||||||||||
| Monoisotopic Mass | 783.409480427 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | InChI=1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3 | ||||||||||||
| InChI Key | GYSCAQFHASJXRS-UHFFFAOYSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Functional Ontology | |||||||||||||
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| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Human Proteins and Enzymes | |||||||||||||
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| Human Pathways | |||||||||||||
| Pathways |
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| Microbial Pathways | |||||||||||||
| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| Health Effects and Bioactivity | |||||||||||||
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| External Links | |||||||||||||
| External Links | Not Available | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
| General References |
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