Record Information
Version2.0
StatusDetected and Quantified
Creation Date2021-05-15 09:19:00 UTC
Update Date2025-10-07 16:06:56 UTC
Metabolite IDMMDBc0019221
Metabolite Identification
Common NameAI-77-F
DescriptionAI-77-F is a metabolite belonging to the chemical class of amicoumacins, which are known for their diverse biological activities. The chemical structure of AI-77-F includes a characteristic isocoumarin core, which is a bicyclic compound that contributes to its bioactivity. This compound has been isolated from the marine fungus Alternaria tenuis Sg17-1, along with other isocoumarins such as AI-77-B (PMID:16915820 ). AI-77-F has been identified in studies focused on anti-quorum sensing (anti-QS) activity, where it was grouped with other amicoumacins, indicating its potential role in microbial communication pathways (PMID:32640925 ). Additionally, it has been noted as a substance produced by Vibrio parahaemolyticus, further emphasizing its relevance in microbial interactions and ecological dynamics (PMID:37512840 ). The unique structural features of AI-77-F, alongside its involvement in these biochemical pathways, highlight its significance in the study of microbial metabolites and their potential applications in biotechnology and medicine.
Structure
Synonyms
ValueSource
2-Hydroxy-N-[1-(8-hydroxy-1-oxo-3,4-dihydro-1H-2-benzopyran-3-yl)-3-methylbutyl]-2-(5-oxo-2,5-dihydrofuran-2-yl)ethanimidateGenerator
Molecular FormulaC20H23NO7
Average Mass389.404
Monoisotopic Mass389.147452085
IUPAC Name2-hydroxy-N-[1-(8-hydroxy-1-oxo-3,4-dihydro-1H-2-benzopyran-3-yl)-3-methylbutyl]-2-(5-oxo-2,5-dihydrofuran-2-yl)acetamide
Traditional Name2-hydroxy-N-[1-(8-hydroxy-1-oxo-3,4-dihydro-2-benzopyran-3-yl)-3-methylbutyl]-2-(5-oxo-2H-furan-2-yl)acetamide
CAS Registry NumberNot Available
SMILES
CC(C)CC(NC(=O)C(O)C1OC(=O)C=C1)C1CC2=CC=CC(O)=C2C(=O)O1
InChI Identifier
InChI=1S/C20H23NO7/c1-10(2)8-12(21-19(25)18(24)14-6-7-16(23)27-14)15-9-11-4-3-5-13(22)17(11)20(26)28-15/h3-7,10,12,14-15,18,22,24H,8-9H2,1-2H3,(H,21,25)
InChI KeyMXZNZZJLGOWQFM-UHFFFAOYSA-N