Showing metabocard for Trypacidin (MMDBc0024593)
Xenobiotic
| Record Information | |||||||||||||
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| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2021-05-15 14:23:44 UTC | ||||||||||||
| Update Date | 2025-10-07 16:07:28 UTC | ||||||||||||
| Metabolite ID | MMDBc0024593 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Trypacidin | ||||||||||||
| Description | Trypacidin is a polyketide metabolite characterized by its complex chemical structure, which features a polycyclic framework typical of many natural products. It is produced by certain fungi, including Aspergillus fumigatus, and is part of a broader class of secondary metabolites that exhibit diverse biological activities. The biosynthetic pathways of trypacidin involve polyketide synthases, which catalyze the condensation of acetyl-CoA and malonyl-CoA units, leading to the formation of its intricate carbon skeleton. Trypacidin has been shown to possess antimicrobial properties, specifically demonstrating antagonistic activity against Vibrio parahaemolyticus, with studies indicating its minimal inhibitory and bactericidal concentrations (PMID:35607390 ). Additionally, trypacidin has been identified alongside other metabolites in various fungal biosynthetic gene clusters, suggesting its role in ecological interactions and potential applications in medicine (PMID:38667937 , PMID:39590656 , PMID:36222427 ). The compound's structural features and biological activities highlight its significance within the realm of natural product chemistry and its potential for further exploration in therapeutic contexts. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C18H16O7 | ||||||||||||
| Average Mass | 344.319 | ||||||||||||
| Monoisotopic Mass | 344.089602855 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | InChI=1S/C18H16O7/c1-9-5-12(22-2)15-13(6-9)25-18(16(15)20)11(17(21)24-4)7-10(19)8-14(18)23-3/h5-8H,1-4H3 | ||||||||||||
| InChI Key | KMZYINVXZDQCKC-UHFFFAOYSA-N | ||||||||||||
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| Functional Ontology | |||||||||||||
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| Physical Properties | |||||||||||||
| State | Expected Solid | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | Not Available | ||||||||||||
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| HMDB ID | Not Available | ||||||||||||
| DrugBank ID | Not Available | ||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||
| FooDB ID | Not Available | ||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||
| Chemspider ID | Not Available | ||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||
| BioCyc ID | Not Available | ||||||||||||
| BiGG ID | Not Available | ||||||||||||
| Wikipedia Link | Not Available | ||||||||||||
| METLIN ID | Not Available | ||||||||||||
| PubChem Compound | Not Available | ||||||||||||
| PDB ID | Not Available | ||||||||||||
| ChEBI ID | Not Available | ||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||
| CMMC Knowledgebase | Not Available | ||||||||||||
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