MiMeDB: Showing metabocard for 12-hydroxynorherqueinone (MMDBc0026293)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2021-05-15 15:57:34 UTC

Update Date

2025-10-07 16:07:39 UTC

Metabolite ID

MMDBc0026293

Metabolite Identification

Common Name

12-hydroxynorherqueinone

Description

12-hydroxynorherqueinone is a phenolic compound belonging to the class of flavonoids. There is limited literature available on this metabolite, indicating that further research is needed to fully understand its biological significance and potential applications.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652305152117572D          

 28 31  0  0  1  0            999 V2000
    2.8579    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9524    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -0.6674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3069   -1.0086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1274    0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6425   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4289    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9441   -0.8205    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6425    1.0799    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5020   -0.3226    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  5  1  1  0  0  0  0
  6  2  1  1  0  0  0
  7  5  1  0  0  0  0
  8  7  1  0  0  0  0
  9  8  2  0  0  0  0
 10  8  1  0  0  0  0
 11  5  2  0  0  0  0
 12  9  1  0  0  0  0
 12 11  1  0  0  0  0
 13  9  1  0  0  0  0
 14 10  2  0  0  0  0
 15 13  2  0  0  0  0
 15 14  1  0  0  0  0
 16 10  1  0  0  0  0
 17  7  2  0  0  0  0
 18  3  1  0  0  0  0
 18  4  1  0  0  0  0
 18  6  1  0  0  0  0
 19 16  1  0  0  0  0
 19 17  1  0  0  0  0
 19 18  1  0  0  0  0
 20 11  1  0  0  0  0
 21 12  2  0  0  0  0
 22 13  1  0  0  0  0
 23 14  1  0  0  0  0
 24 15  1  0  0  0  0
 25 16  2  0  0  0  0
 19 26  1  6  0  0  0
 27  6  1  0  0  0  0
 27 17  1  0  0  0  0
  6 28  1  6  0  0  0
M  END


  Mrv1652305152117572D          

 28 31  0  0  1  0            999 V2000
    2.8579    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9524    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -0.6674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3069   -1.0086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1274    0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6425   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4289    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9441   -0.8205    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6425    1.0799    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5020   -0.3226    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  5  1  1  0  0  0  0
  6  2  1  1  0  0  0
  7  5  1  0  0  0  0
  8  7  1  0  0  0  0
  9  8  2  0  0  0  0
 10  8  1  0  0  0  0
 11  5  2  0  0  0  0
 12  9  1  0  0  0  0
 12 11  1  0  0  0  0
 13  9  1  0  0  0  0
 14 10  2  0  0  0  0
 15 13  2  0  0  0  0
 15 14  1  0  0  0  0
 16 10  1  0  0  0  0
 17  7  2  0  0  0  0
 18  3  1  0  0  0  0
 18  4  1  0  0  0  0
 18  6  1  0  0  0  0
 19 16  1  0  0  0  0
 19 17  1  0  0  0  0
 19 18  1  0  0  0  0
 20 11  1  0  0  0  0
 21 12  2  0  0  0  0
 22 13  1  0  0  0  0
 23 14  1  0  0  0  0
 24 15  1  0  0  0  0
 25 16  2  0  0  0  0
 19 26  1  6  0  0  0
 27  6  1  0  0  0  0
 27 17  1  0  0  0  0
  6 28  1  6  0  0  0
M  END
> <DATABASE_ID>
MMDBc0026293

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@@]1(C)OC2=C3C(C)=C(O)C(=O)C4=C3C(=C(O)C(O)=C4O)C(=O)[C@]2(O)C1(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C19H18O8/c1-5-7-8-9(12(21)11(5)20)13(22)15(24)14(23)10(8)16(25)19(26)17(7)27-6(2)18(19,3)4/h6,20,22-24,26H,1-4H3/t6-,19+/m0/s1

> <INCHI_KEY>
OHYBFPRPSLPQEO-INMOSUBGSA-N

> <FORMULA>
C19H18O8

> <MOLECULAR_WEIGHT>
374.345

> <EXACT_MASS>
374.10016754

> <JCHEM_ACCEPTOR_COUNT>
8

> <JCHEM_ATOM_COUNT>
45

> <JCHEM_AVERAGE_POLARIZABILITY>
36.27442640262949

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(12S,14S)-2,3,4,7,14-pentahydroxy-8,12,13,13-tetramethyl-11-oxatetracyclo[7.6.1.0^{5,16}.0^{10,14}]hexadeca-1,3,5(16),7,9-pentaene-6,15-dione

> <ALOGPS_LOGP>
1.80

> <JCHEM_LOGP>
1.8424824533333328

> <ALOGPS_LOGS>
-2.32

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
7.870471805833214

> <JCHEM_PKA_STRONGEST_ACIDIC>
6.694397065528657

> <JCHEM_PKA_STRONGEST_BASIC>
-4.150908882700777

> <JCHEM_POLAR_SURFACE_AREA>
144.51999999999998

> <JCHEM_REFRACTIVITY>
95.65809999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.78e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(12S,14S)-2,3,4,7,14-pentahydroxy-8,12,13,13-tetramethyl-11-oxatetracyclo[7.6.1.0^{5,16}.0^{10,14}]hexadeca-1,3,5(16),7,9-pentaene-6,15-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 15-MAY-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   15-MAY-21         0                                  
HETATM    1  C   UNK     0       5.335   4.620   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       9.245   0.770   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       8.133  -1.246   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       6.173  -1.883   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.001   3.850   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       7.705   0.770   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       2.667   4.620   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.334   3.850   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       0.000  -0.000   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.799  -0.476   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       5.335  -0.000   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       2.667   6.160   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0      -0.000   4.620   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0      -1.334   2.310   0.000  0.00  0.00           O+0
HETATM   23  O   UNK     0       1.334  -2.310   0.000  0.00  0.00           O+0
HETATM   24  O   UNK     0      -1.334  -0.770   0.000  0.00  0.00           O+0
HETATM   25  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0       5.496  -1.532   0.000  0.00  0.00           O+0
HETATM   27  O   UNK     0       6.799   2.016   0.000  0.00  0.00           O+0
HETATM   28  H   UNK     0       8.404  -0.602   0.000  0.00  0.00           H+0
CONECT    1    5                                                            
CONECT    2    6                                                            
CONECT    3   18                                                            
CONECT    4   18                                                            
CONECT    5    1    7   11                                                  
CONECT    6    2   18   27   28                                             
CONECT    7    5    8   17                                                  
CONECT    8    7    9   10                                                  
CONECT    9    8   12   13                                                  
CONECT   10    8   14   16                                                  
CONECT   11    5   12   20                                                  
CONECT   12    9   11   21                                                  
CONECT   13    9   15   22                                                  
CONECT   14   10   15   23                                                  
CONECT   15   13   14   24                                                  
CONECT   16   10   19   25                                                  
CONECT   17    7   19   27                                                  
CONECT   18    3    4    6   19                                             
CONECT   19   16   17   18   26                                             
CONECT   20   11                                                            
CONECT   21   12                                                            
CONECT   22   13                                                            
CONECT   23   14                                                            
CONECT   24   15                                                            
CONECT   25   16                                                            
CONECT   26   19                                                            
CONECT   27    6   17                                                       
CONECT   28    6                                                            
MASTER        0    0    0    0    0    0    0    0   28    0   62    0
END

Synonyms

Not Available

Molecular Formula

C₁₉H₁₈O₈

Average Mass

374.345

Monoisotopic Mass

374.10016754

IUPAC Name

(12S,14S)-2,3,4,7,14-pentahydroxy-8,12,13,13-tetramethyl-11-oxatetracyclo[7.6.1.0^{5,16}.0^{10,14}]hexadeca-1,3,5(16),7,9-pentaene-6,15-dione

Traditional Name

(12S,14S)-2,3,4,7,14-pentahydroxy-8,12,13,13-tetramethyl-11-oxatetracyclo[7.6.1.0^{5,16}.0^{10,14}]hexadeca-1,3,5(16),7,9-pentaene-6,15-dione

CAS Registry Number

Not Available

SMILES

[H][C@@]1(C)OC2=C3C(C)=C(O)C(=O)C4=C3C(=C(O)C(O)=C4O)C(=O)[C@]2(O)C1(C)C

InChI Identifier

InChI=1S/C19H18O8/c1-5-7-8-9(12(21)11(5)20)13(22)15(24)14(23)10(8)16(25)19(26)17(7)27-6(2)18(19,3)4/h6,20,22-24,26H,1-4H3/t6-,19+/m0/s1

InChI Key

OHYBFPRPSLPQEO-INMOSUBGSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as naphthofurans. Naphthofurans are compounds containing a furan ring fused to a naphthalene moiety. Furan is a 5 membered- ring aromatic ring with four carbon and one oxygen atoms. Naphthalene is a polycyclic aromatic hydrocarbon made up of two fused benzene rings.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Naphthofurans

Sub Class

Not Available

Direct Parent

Naphthofurans

Alternative Parents

Substituents

Naphthofuran
2-naphthol
Naphthalene
Aryl alkyl ketone
Aryl ketone
Benzenoid
Vinylogous acid
Tetrahydrofuran
Tertiary alcohol
Ketone
Oxacycle
Polyol
Enol
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	1.78 g/L	ALOGPS
logP	1.8	ALOGPS
logP	1.84	ChemAxon
logS	-2.3	ALOGPS
pKa (Strongest Acidic)	6.69	ChemAxon
pKa (Strongest Basic)	-4.2	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	144.52 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	95.66 m³·mol⁻¹	ChemAxon
Polarizability	36.27 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (void)	2025-10-23	11.8
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (void)	2025-10-23	25.3
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-23	538.2
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-23	959.9
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-23	915.3
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (eluted)	2025-10-23	322.1
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-23	2540.9
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-23	86.6
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-23	621.7
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-23	398.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-23	241.7
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-23	159.2
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-23	140.0
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (void)	2025-10-23	109.9
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-23	531.5
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-23	139.5
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-23	479.1
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-23	1805.0
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-23	1113.6

Retention Indices

Chromatography Type	Peak Label	SMILES	Stationary Phase	Deposition Date	Retention Index
Gas Chromatography	12-hydroxynorherqueinone_TMS_1	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	3515.1
Gas Chromatography	12-hydroxynorherqueinone_TMS_2	CC1=C(O)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	2899.9
Gas Chromatography	12-hydroxynorherqueinone_TMS_3	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1819.13
Gas Chromatography	12-hydroxynorherqueinone_TMS_4	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	2647.62
Gas Chromatography	12-hydroxynorherqueinone_TMS_5	CC1=C(O)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2291.67
Gas Chromatography	12-hydroxynorherqueinone_TMS_6	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	2667.36
Gas Chromatography	12-hydroxynorherqueinone_TMS_7	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1788.89
Gas Chromatography	12-hydroxynorherqueinone_TMS_8	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1921.5
Gas Chromatography	12-hydroxynorherqueinone_TMS_9	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1439.34
Gas Chromatography	12-hydroxynorherqueinone_TMS_10	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1575.09
Gas Chromatography	12-hydroxynorherqueinone_TMS_11	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1793.44
Gas Chromatography	12-hydroxynorherqueinone_TMS_12	CC1=C(O)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2553.75
Gas Chromatography	12-hydroxynorherqueinone_TMS_13	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1140.02
Gas Chromatography	12-hydroxynorherqueinone_TMS_14	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2595.87
Gas Chromatography	12-hydroxynorherqueinone_TMS_15	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2512.75
Gas Chromatography	12-hydroxynorherqueinone_TMS_16	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1667.2
Gas Chromatography	12-hydroxynorherqueinone_TMS_17	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	755.021
Gas Chromatography	12-hydroxynorherqueinone_TMS_18	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2818.83
Gas Chromatography	12-hydroxynorherqueinone_TMS_19	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	614.257
Gas Chromatography	12-hydroxynorherqueinone_TMS_20	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1520.1
Gas Chromatography	12-hydroxynorherqueinone_TMS_21	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1179.12
Gas Chromatography	12-hydroxynorherqueinone_TMS_22	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	2407.09
Gas Chromatography	12-hydroxynorherqueinone_TMS_23	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2215.38
Gas Chromatography	12-hydroxynorherqueinone_TMS_24	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1682.43
Gas Chromatography	12-hydroxynorherqueinone_TMS_25	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	2189.13
Gas Chromatography	12-hydroxynorherqueinone_TMS_26	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard non polar	2025-10-23	1941.68
Gas Chromatography	12-hydroxynorherqueinone_TMS_27	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1351.61
Gas Chromatography	12-hydroxynorherqueinone_TMS_28	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1775.13
Gas Chromatography	12-hydroxynorherqueinone_TMS_29	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1791.83
Gas Chromatography	12-hydroxynorherqueinone_TMS_30	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	1823.43
Gas Chromatography	12-hydroxynorherqueinone_TMS_31	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard non polar	2025-10-23	824.329
Gas Chromatography	12-hydroxynorherqueinone_TMS_1	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	3137.08
Gas Chromatography	12-hydroxynorherqueinone_TMS_2	CC1=C(O)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2535.61
Gas Chromatography	12-hydroxynorherqueinone_TMS_3	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	1230.9
Gas Chromatography	12-hydroxynorherqueinone_TMS_4	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2699.68
Gas Chromatography	12-hydroxynorherqueinone_TMS_5	CC1=C(O)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2440.74
Gas Chromatography	12-hydroxynorherqueinone_TMS_6	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2542.44
Gas Chromatography	12-hydroxynorherqueinone_TMS_7	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2299.8
Gas Chromatography	12-hydroxynorherqueinone_TMS_8	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	1847.06
Gas Chromatography	12-hydroxynorherqueinone_TMS_9	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2337.02
Gas Chromatography	12-hydroxynorherqueinone_TMS_10	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2228.54
Gas Chromatography	12-hydroxynorherqueinone_TMS_11	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	3126.83
Gas Chromatography	12-hydroxynorherqueinone_TMS_12	CC1=C(O)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1968.39
Gas Chromatography	12-hydroxynorherqueinone_TMS_13	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	1791.94
Gas Chromatography	12-hydroxynorherqueinone_TMS_14	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2979.87
Gas Chromatography	12-hydroxynorherqueinone_TMS_15	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1059.57
Gas Chromatography	12-hydroxynorherqueinone_TMS_16	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	3058.24
Gas Chromatography	12-hydroxynorherqueinone_TMS_17	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2286.5
Gas Chromatography	12-hydroxynorherqueinone_TMS_18	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1834.68
Gas Chromatography	12-hydroxynorherqueinone_TMS_19	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	2405.37
Gas Chromatography	12-hydroxynorherqueinone_TMS_20	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2067.9
Gas Chromatography	12-hydroxynorherqueinone_TMS_21	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1118.67
Gas Chromatography	12-hydroxynorherqueinone_TMS_22	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	1174.61
Gas Chromatography	12-hydroxynorherqueinone_TMS_23	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1581.32
Gas Chromatography	12-hydroxynorherqueinone_TMS_24	CC1=C(O)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	879.97
Gas Chromatography	12-hydroxynorherqueinone_TMS_25	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	1858.38
Gas Chromatography	12-hydroxynorherqueinone_TMS_26	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O)C3=O	standard polar	2025-10-23	3514.76
Gas Chromatography	12-hydroxynorherqueinone_TMS_27	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2581.41
Gas Chromatography	12-hydroxynorherqueinone_TMS_28	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2085.92
Gas Chromatography	12-hydroxynorherqueinone_TMS_29	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2360.32
Gas Chromatography	12-hydroxynorherqueinone_TMS_30	CC1=C(O)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	3.85761
Gas Chromatography	12-hydroxynorherqueinone_TMS_31	CC1=C(O[Si](C)(C)C)C(=O)C2=C(O[Si](C)(C)C)C(O[Si](C)(C)C)=C(O[Si](C)(C)C)C3=C2C1=C1O[C@@H](C)C(C)(C)[C@@]1(O[Si](C)(C)C)C3=O	standard polar	2025-10-23	2396.31

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces	Metabolic reconstruction

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

73930392

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

146682911

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

van Santen JA, Poynton EF, Iskakova D, McMann E, Alsup TA, Clark TN, Fergusson CH, Fewer DP, Hughes AH, McCadden CA, Parra J, Soldatou S, Rudolf JD, Janssen EM, Duncan KR, Linington RG: The Natural Products Atlas 2.0: a database of microbially-derived natural products. Nucleic Acids Res. 2022 Jan 7;50(D1):D1317-D1323. doi: 10.1093/nar/gkab941. [PubMed:34718710 ]

Showing metabocard for 12-hydroxynorherqueinone (MMDBc0026293)

MOL for #<Metabolite:0x00007fade8116500>

3D MOL for #<Metabolite:0x00007fade8116500>

3D SDF for #<Metabolite:0x00007fade8116500>

3D-SDF for #<Metabolite:0x00007fade8116500>

PDB for #<Metabolite:0x00007fade8116500>

3D PDB for #<Metabolite:0x00007fade8116500>

SMILES for #<Metabolite:0x00007fade8116500>

INCHI for #<Metabolite:0x00007fade8116500>

Structure for #<Metabolite:0x00007fade8116500>

3D Structure for #<Metabolite:0x00007fade8116500>