Showing metabocard for Aspergillic acid (MMDBc0028235)
Xenobiotic
| Record Information | |||||||||||||
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2021-05-15 17:52:20 UTC | ||||||||||||
| Update Date | 2025-10-07 16:07:50 UTC | ||||||||||||
| Metabolite ID | MMDBc0028235 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Aspergillic acid | ||||||||||||
| Description | Aspergillic acid is a hydroxamic acid-containing pyrazinone metabolite belonging to the class of iron-binding compounds. Its chemical structure features a complex arrangement that includes a hydroxamic acid functional group, which is crucial for its metal chelation properties. Aspergillic acid is primarily synthesized in the Aspergillus genus, with the biosynthetic pathway involving the asa gene cluster, which has been shown to be responsible for its production (PMID:37746228 ). In various studies, the upregulation of aspergillic acid has been observed in specific mutant strains, indicating its role in metabolic pathways alongside other metabolites such as aflatoxin and kojic acid (PMID:39452671 ). Additionally, its synthesis is influenced by genetic factors, as demonstrated by the profiling of mutants lacking certain non-ribosomal synthetases (PMID:40262766 ). Aspergillic acid's involvement in metabolic interactions is further highlighted by its varying levels in the presence of bacteria and other environmental factors (PMID:38980562 ). Overall, aspergillic acid serves as an important component in the metabolic landscape of Aspergillus species, contributing to the diversity of secondary metabolites produced by these fungi. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C12H20N2O2 | ||||||||||||
| Average Mass | 224.304 | ||||||||||||
| Monoisotopic Mass | 224.152477892 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | InChI=1S/C12H20N2O2/c1-5-9(4)11-7-13-10(6-8(2)3)12(15)14(11)16/h7-9,16H,5-6H2,1-4H3 | ||||||||||||
| InChI Key | IUZCDJYHMMWBBE-UHFFFAOYSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Functional Ontology | |||||||||||||
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| Physical Properties | |||||||||||||
| State | Expected Solid | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| HMDB ID | Not Available | ||||||||||||
| DrugBank ID | Not Available | ||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||
| FooDB ID | Not Available | ||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||
| Chemspider ID | Not Available | ||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||
| BioCyc ID | Not Available | ||||||||||||
| BiGG ID | Not Available | ||||||||||||
| Wikipedia Link | Not Available | ||||||||||||
| METLIN ID | Not Available | ||||||||||||
| PubChem Compound | Not Available | ||||||||||||
| PDB ID | Not Available | ||||||||||||
| ChEBI ID | Not Available | ||||||||||||
| CMMC Knowledgebase | Not Available | ||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||
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| Synthesis Reference | Not Available | ||||||||||||
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