MiMeDB: Showing metabocard for ergosteryl oleate (MMDBc0033023)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:31:31 UTC

Update Date

2025-10-07 16:07:53 UTC

Metabolite ID

MMDBc0033023

Metabolite Identification

Common Name

ergosteryl oleate

Description

Ergosteryl oleate is a sterol ester belonging to the chemical class of lipids. It consists of an oleic acid moiety esterified to ergosterol, a sterol found in fungal membranes. The chemical structure features a long hydrocarbon chain from oleic acid linked to the hydroxyl group of ergosterol, forming an ester bond. In biological pathways, ergosteryl oleate is involved in lipid metabolism, particularly in the context of cholesterol and sterol homeostasis. It is synthesized through the action of acyl-CoA:cholesterol acyltransferase (ACAT), which catalyzes the esterification of cholesterol and ergosterol. Notably, research indicates that human ACAT expressed in sat1 sat2 mutant cells can catalyze the formation of ergosteryl oleate in vitro, although this process is less efficient than that mediated by yeast acyl-CoA:sterol acyltransferase (ASAT) in wild-type cells, achieving only about 8% of the latter's activity in vivo (PMID:8798656 ). This suggests that ergosteryl oleate may play a role in lipid storage and membrane dynamics, although its precise biological functions remain to be fully elucidated.

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02241222242D          

 51 54  0  0  1  0            999 V2000
   -2.1733   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -1.6509    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1733   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.8118    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587    0.3930    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279    0.8130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718    0.3930    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6718   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4565   -0.6719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9228   -0.0188    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    0.6494    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6718    1.2404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.0033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718   -1.2469    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1796    1.0539    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.0818    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7587   -1.2405    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7421    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8855    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    0.6718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1710    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    1.4968    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0289    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5999    1.9093    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5999    2.7343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.9068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7713   -7.8569    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0570   -8.2694    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9147   -3.3194    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3436   -3.3194    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9146   -4.1444    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2002   -4.5570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2002   -5.3819    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4858   -5.7944    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4858   -6.6195    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7713   -7.0320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6576   -7.8569    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3720   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0865   -7.8570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8010   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5155   -7.8570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2299   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9444   -7.8571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6589   -8.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 11 10  1  0  0  0  0
 14 10  1  0  0  0  0
  9 10  1  0  0  0  0
 10 15  1  1  0  0  0
 23 11  1  0  0  0  0
 12 11  1  0  0  0  0
 11 17  1  6  0  0  0
  8 20  1  0  0  0  0
  7 20  1  0  0  0  0
 23 20  1  0  0  0  0
 24 23  2  0  0  0  0
  5  7  1  0  0  0  0
  7 16  1  1  0  0  0
  1  7  1  0  0  0  0
 13 14  1  0  0  0  0
 29 14  1  0  0  0  0
 14 18  1  6  0  0  0
  8  9  1  0  0  0  0
 13 12  1  0  0  0  0
  6 24  1  0  0  0  0
  4  5  1  0  0  0  0
  6  5  2  0  0  0  0
  2  1  1  0  0  0  0
  3  4  1  0  0  0  0
  3  2  1  0  0  0  0
  3 19  1  1  0  0  0
 20 21  1  6  0  0  0
 29 22  1  6  0  0  0
 28 25  2  0  0  0  0
 31 25  1  0  0  0  0
 26 31  1  0  0  0  0
 27 26  1  0  0  0  0
 30 26  1  0  0  0  0
 28 29  1  0  0  0  0
 31 32  1  6  0  0  0
 19 33  1  0  0  0  0
 33 36  1  0  0  0  0
 33 37  2  0  0  0  0
 43 34  1  0  0  0  0
 34 35  2  0  0  0  0
 44 35  1  0  0  0  0
 36 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 45 44  1  0  0  0  0
 46 45  1  0  0  0  0
 47 46  1  0  0  0  0
 48 47  1  0  0  0  0
 49 48  1  0  0  0  0
 50 49  1  0  0  0  0
 51 50  1  0  0  0  0
M  END


  Mrv0541 02241222242D          

 51 54  0  0  1  0            999 V2000
   -2.1733   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -1.6509    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.1733   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.8118    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587    0.3930    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279    0.8130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718    0.3930    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6718   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4565   -0.6719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9228   -0.0188    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    0.6494    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6718    1.2404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.0033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718   -1.2469    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1796    1.0539    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.0818    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7587   -1.2405    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7421    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8855    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    0.6718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1710    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    1.4968    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0289    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5999    1.9093    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5999    2.7343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.9068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7713   -7.8569    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0570   -8.2694    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9147   -3.3194    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3436   -3.3194    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9146   -4.1444    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2002   -4.5570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2002   -5.3819    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4858   -5.7944    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4858   -6.6195    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7713   -7.0320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6576   -7.8569    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3720   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0865   -7.8570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8010   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5155   -7.8570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2299   -8.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9444   -7.8571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6589   -8.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 11 10  1  0  0  0  0
 14 10  1  0  0  0  0
  9 10  1  0  0  0  0
 10 15  1  1  0  0  0
 23 11  1  0  0  0  0
 12 11  1  0  0  0  0
 11 17  1  6  0  0  0
  8 20  1  0  0  0  0
  7 20  1  0  0  0  0
 23 20  1  0  0  0  0
 24 23  2  0  0  0  0
  5  7  1  0  0  0  0
  7 16  1  1  0  0  0
  1  7  1  0  0  0  0
 13 14  1  0  0  0  0
 29 14  1  0  0  0  0
 14 18  1  6  0  0  0
  8  9  1  0  0  0  0
 13 12  1  0  0  0  0
  6 24  1  0  0  0  0
  4  5  1  0  0  0  0
  6  5  2  0  0  0  0
  2  1  1  0  0  0  0
  3  4  1  0  0  0  0
  3  2  1  0  0  0  0
  3 19  1  1  0  0  0
 20 21  1  6  0  0  0
 29 22  1  6  0  0  0
 28 25  2  0  0  0  0
 31 25  1  0  0  0  0
 26 31  1  0  0  0  0
 27 26  1  0  0  0  0
 30 26  1  0  0  0  0
 28 29  1  0  0  0  0
 31 32  1  6  0  0  0
 19 33  1  0  0  0  0
 33 36  1  0  0  0  0
 33 37  2  0  0  0  0
 43 34  1  0  0  0  0
 34 35  2  0  0  0  0
 44 35  1  0  0  0  0
 36 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 45 44  1  0  0  0  0
 46 45  1  0  0  0  0
 47 46  1  0  0  0  0
 48 47  1  0  0  0  0
 49 48  1  0  0  0  0
 50 49  1  0  0  0  0
 51 50  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0033023

> <DATABASE_NAME>
MIME

> <SMILES>
CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H]1CC[C@@]2(C)C(=CC=C3[C@]4([H])CC[C@]([H])([C@H](C)\C=C\[C@H](C)C(C)C)[C@@]4(C)CC[C@]23[H])C1

> <INCHI_IDENTIFIER>
InChI=1S/C46H76O2/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-44(47)48-39-30-32-45(6)38(34-39)26-27-40-42-29-28-41(46(42,7)33-31-43(40)45)37(5)25-24-36(4)35(2)3/h15-16,24-27,35-37,39,41-43H,8-14,17-23,28-34H2,1-7H3/b16-15-,25-24+/t36-,37+,39-,41+,42-,43-,45-,46+/m0/s1

> <INCHI_KEY>
VVZNLLXLOKRQPH-NZIRWOIASA-N

> <FORMULA>
C46H76O2

> <MOLECULAR_WEIGHT>
661.0944

> <EXACT_MASS>
660.584531676

> <JCHEM_ACCEPTOR_COUNT>
1

> <JCHEM_AVERAGE_POLARIZABILITY>
86.2539288679234

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1S,2R,5S,11R,14R,15R)-14-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-7,9-dien-5-yl (9Z)-octadec-9-enoate

> <ALOGPS_LOGP>
10.93

> <JCHEM_LOGP>
14.080676564666668

> <ALOGPS_LOGS>
-7.91

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-7.042198905878133

> <JCHEM_POLAR_SURFACE_AREA>
26.3

> <JCHEM_REFRACTIVITY>
211.0417

> <JCHEM_ROTATABLE_BOND_COUNT>
21

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
8.08e-06 g/l

> <JCHEM_TRADITIONAL_IUPAC>
ergosteryl oleate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  C   UNK     0      -4.057  -0.775   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -5.406  -1.515   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -5.406  -3.082   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.057  -3.851   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -2.751  -3.082   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.416  -3.851   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -2.751  -1.515   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -1.416   0.734   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -0.052   1.518   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.254   0.734   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.254  -0.775   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.719  -1.254   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       3.589  -0.035   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.719   1.212   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.254   2.315   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -2.751  -0.006   0.000  0.00  0.00           C+0
HETATM   17  H   UNK     0       1.254  -2.328   0.000  0.00  0.00           H+0
HETATM   18  H   UNK     0       4.069   1.967   0.000  0.00  0.00           H+0
HETATM   19  O   UNK     0      -6.774  -3.886   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      -1.416  -0.775   0.000  0.00  0.00           C+0
HETATM   21  H   UNK     0      -1.416  -2.316   0.000  0.00  0.00           H+0
HETATM   22  C   UNK     0       1.385   3.564   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -0.052  -1.515   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -0.052  -3.082   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       5.386   2.794   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       8.054   2.794   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       8.054   1.254   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       4.053   3.564   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       2.719   2.794   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       9.387   3.564   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       6.720   3.564   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       6.720   5.104   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      -6.774  -5.426   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      -1.440 -14.666   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      -0.106 -15.436   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      -5.441  -6.196   0.000  0.00  0.00           C+0
HETATM   37  O   UNK     0      -8.108  -6.196   0.000  0.00  0.00           O+0
HETATM   38  C   UNK     0      -5.441  -7.736   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      -4.107  -8.506   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0      -4.107 -10.046   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0      -2.773 -10.816   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      -2.773 -12.356   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      -1.440 -13.126   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0       1.228 -14.666   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0       2.561 -15.436   0.000  0.00  0.00           C+0
HETATM   46  C   UNK     0       3.895 -14.666   0.000  0.00  0.00           C+0
HETATM   47  C   UNK     0       5.229 -15.436   0.000  0.00  0.00           C+0
HETATM   48  C   UNK     0       6.562 -14.666   0.000  0.00  0.00           C+0
HETATM   49  C   UNK     0       7.896 -15.436   0.000  0.00  0.00           C+0
HETATM   50  C   UNK     0       9.230 -14.667   0.000  0.00  0.00           C+0
HETATM   51  C   UNK     0      10.563 -15.437   0.000  0.00  0.00           C+0
CONECT    1    7    2                                                       
CONECT    2    1    3                                                       
CONECT    3    4    2   19                                                  
CONECT    4    5    3                                                       
CONECT    5    7    4    6                                                  
CONECT    6   24    5                                                       
CONECT    7   20    5   16    1                                             
CONECT    8   20    9                                                       
CONECT    9   10    8                                                       
CONECT   10   11   14    9   15                                             
CONECT   11   10   23   12   17                                             
CONECT   12   11   13                                                       
CONECT   13   14   12                                                       
CONECT   14   10   13   29   18                                             
CONECT   15   10                                                            
CONECT   16    7                                                            
CONECT   17   11                                                            
CONECT   18   14                                                            
CONECT   19    3   33                                                       
CONECT   20    8    7   23   21                                             
CONECT   21   20                                                            
CONECT   22   29                                                            
CONECT   23   11   20   24                                                  
CONECT   24   23    6                                                       
CONECT   25   28   31                                                       
CONECT   26   31   27   30                                                  
CONECT   27   26                                                            
CONECT   28   25   29                                                       
CONECT   29   14   22   28                                                  
CONECT   30   26                                                            
CONECT   31   25   26   32                                                  
CONECT   32   31                                                            
CONECT   33   19   36   37                                                  
CONECT   34   43   35                                                       
CONECT   35   34   44                                                       
CONECT   36   33   38                                                       
CONECT   37   33                                                            
CONECT   38   36   39                                                       
CONECT   39   38   40                                                       
CONECT   40   39   41                                                       
CONECT   41   40   42                                                       
CONECT   42   41   43                                                       
CONECT   43   34   42                                                       
CONECT   44   35   45                                                       
CONECT   45   44   46                                                       
CONECT   46   45   47                                                       
CONECT   47   46   48                                                       
CONECT   48   47   49                                                       
CONECT   49   48   50                                                       
CONECT   50   49   51                                                       
CONECT   51   50                                                            
MASTER        0    0    0    0    0    0    0    0   51    0  108    0
END

Synonyms

Value	Source
Ergosteryl oleic acid	Generator

Molecular Formula

C₄₆H₇₆O₂

Average Mass

661.0944

Monoisotopic Mass

660.584531676

IUPAC Name

(1S,2R,5S,11R,14R,15R)-14-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-7,9-dien-5-yl (9Z)-octadec-9-enoate

Traditional Name

ergosteryl oleate

CAS Registry Number

Not Available

SMILES

CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H]1CC[C@@]2(C)C(=CC=C3[C@]4([H])CC[C@]([H])([C@H](C)\C=C\[C@H](C)C(C)C)[C@@]4(C)CC[C@]23[H])C1

InChI Identifier

InChI=1S/C46H76O2/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-44(47)48-39-30-32-45(6)38(34-39)26-27-40-42-29-28-41(46(42,7)33-31-43(40)45)37(5)25-24-36(4)35(2)3/h15-16,24-27,35-37,39,41-43H,8-14,17-23,28-34H2,1-7H3/b16-15-,25-24+/t36-,37+,39-,41+,42-,43-,45-,46+/m0/s1

InChI Key

VVZNLLXLOKRQPH-NZIRWOIASA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as steroid esters. Steroid esters are compounds containing a steroid moiety which bears a carboxylic acid ester group.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Steroid esters

Direct Parent

Steroid esters

Alternative Parents

Substituents

Steroid ester
Delta-7-steroid
Delta-5-steroid
Carboxylic acid ester
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

ergosteryl ester (CHEBI:52377 )
Ergosterols and C24-methyl derivatives (LMST01031010 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	8.1e-06 g/L	ALOGPS
logP	10.93	ALOGPS
logP	14.08	ChemAxon
logS	-7.9	ALOGPS
pKa (Strongest Basic)	-7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	1	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	26.3 Å²	ChemAxon
Rotatable Bond Count	21	ChemAxon
Refractivity	211.04 m³·mol⁻¹	ChemAxon
Polarizability	86.25 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0400-3154039000-1154c00a631f32d997af	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-00nk-6398041000-fdbcc0aec3b1c2873db4	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-008i-9386040000-56265571bbb57adea3e2	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0a4i-0024009000-17165970be65d97f8f84	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0002-0059103000-0ab1c6b0a7209eb31a8d	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-002g-3029000000-af51e226dda43a4c551c	2016-09-12	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (void)	2025-10-24	208.5
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (void)	2025-10-24	65.3
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-24	1331.1
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-24	1818.0
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-24	2295.2
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (eluted)	2025-10-24	1476.3
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	6059.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-24	133.7
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-24	703.8
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	1968.6
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-24	1281.8
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	710.3
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	554.1
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (void)	2025-10-24	11.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (void)	2025-10-24	763.2
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	1185.4
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	1033.9
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-24	3607.5
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-24	4369.4

Retention Indices

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

25271616

PDB ID

Not Available

ChEBI ID

52377

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Zweytick D, Leitner E, Kohlwein SD, Yu C, Rothblatt J, Daum G: Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur J Biochem. 2000 Feb;267(4):1075-82. doi: 10.1046/j.1432-1327.2000.01103.x. [PubMed:10672016 ]
Herrgard MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Bluthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novere N, Li P, Liebermeister W, Mo ML, Oliveira AP, Petranovic D, Pettifer S, Simeonidis E, Smallbone K, Spasic I, Weichart D, Brent R, Broomhead DS, Westerhoff HV, Kirdar B, Penttila M, Klipp E, Palsson BO, Sauer U, Oliver SG, Mendes P, Nielsen J, Kell DB: A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat Biotechnol. 2008 Oct;26(10):1155-60. doi: 10.1038/nbt1492. [PubMed:18846089 ]

Showing metabocard for ergosteryl oleate (MMDBc0033023)

MOL for #<Metabolite:0x00007fc93e1c4008>

3D MOL for #<Metabolite:0x00007fc93e1c4008>

3D SDF for #<Metabolite:0x00007fc93e1c4008>

3D-SDF for #<Metabolite:0x00007fc93e1c4008>

PDB for #<Metabolite:0x00007fc93e1c4008>

3D PDB for #<Metabolite:0x00007fc93e1c4008>

SMILES for #<Metabolite:0x00007fc93e1c4008>

INCHI for #<Metabolite:0x00007fc93e1c4008>

Structure for #<Metabolite:0x00007fc93e1c4008>

3D Structure for #<Metabolite:0x00007fc93e1c4008>