MiMeDB: Showing metabocard for 11a-hydroxytigecycline (MMDBc0055155)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2022-06-17 19:44:56 UTC

Update Date

2025-10-07 16:08:58 UTC

Metabolite ID

MMDBc0055155

Metabolite Identification

Common Name

11a-hydroxytigecycline

Description

11a-hydroxytigecycline is a member of the tetracycline class of antibiotics, specifically a metabolite of tigecycline. Chemically, it is characterized by the presence of a hydroxyl group at the 11a position, which alters its interaction with biological targets. This modification affects its ability to inhibit protein translation, as evidenced by the fact that 11a-hydroxytigecycline has a weakened ability to form a complex with the ribosome compared to its parent compound, tigecycline (PMID:16128584 ). Additionally, 11a-hydroxytigecycline forms a weaker complex with magnesium, an essential cofactor for binding tetracycline to the ribosome, which is critical for its antibacterial activity (PMID:16128584 ). The enzymatic modification of tigecycline to 11a-hydroxytigecycline by TetX contributes to antibiotic resistance, highlighting the importance of chemical structure in determining the efficacy of antibiotic agents and their interactions in biological pathways related to protein synthesis.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652306172221442D          

 46 49  0  0  1  0            999 V2000
    8.5737   -3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2717   -2.1730    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4467   -3.6020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
    7.1447   -2.4750    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    2.0625    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
 12  8  1  0  0  0  0
 12  9  1  0  0  0  0
 13  8  1  0  0  0  0
 14  9  1  0  0  0  0
 15 10  2  0  0  0  0
 16 10  1  0  0  0  0
 16 13  2  0  0  0  0
 17 11  1  0  0  0  0
 18 13  1  0  0  0  0
 20 14  1  0  0  0  0
 21 15  1  0  0  0  0
 21 18  2  0  0  0  0
 22 19  2  0  0  0  0
 22 20  1  0  0  0  0
 23 18  1  0  0  0  0
 24 19  1  0  0  0  0
 25 19  1  0  0  0  0
 27  1  1  0  0  0  0
 27  2  1  0  0  0  0
 27  3  1  0  0  0  0
 28 12  1  0  0  0  0
 28 23  1  0  0  0  0
 28 26  1  0  0  0  0
 29 14  1  0  0  0  0
 29 24  1  0  0  0  0
 29 26  1  0  0  0  0
 30 25  2  0  0  0  0
 31 11  1  0  0  0  0
 31 27  1  0  0  0  0
 32 15  1  4  0  0  0
 32 17  2  0  0  0  0
 33  4  1  0  0  0  0
 33  5  1  0  0  0  0
 33 16  1  0  0  0  0
 34  6  1  0  0  0  0
 34  7  1  0  0  0  0
 20 34  1  1  0  0  0
 35 17  1  0  0  0  0
 36 21  1  0  0  0  0
 37 22  1  0  0  0  0
 38 23  2  0  0  0  0
 39 24  2  0  0  0  0
 40 25  1  0  0  0  0
 41 26  2  0  0  0  0
 28 42  1  1  0  0  0
 29 43  1  1  0  0  0
 12 44  1  1  0  0  0
 14 45  1  1  0  0  0
 20 46  1  6  0  0  0
M  CHG  1  30   1
M  END


  Mrv1652306172221442D          

 46 49  0  0  1  0            999 V2000
    8.5737   -3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2717   -2.1730    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4467   -3.6020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
    7.1447   -2.4750    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    2.0625    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
 12  8  1  0  0  0  0
 12  9  1  0  0  0  0
 13  8  1  0  0  0  0
 14  9  1  0  0  0  0
 15 10  2  0  0  0  0
 16 10  1  0  0  0  0
 16 13  2  0  0  0  0
 17 11  1  0  0  0  0
 18 13  1  0  0  0  0
 20 14  1  0  0  0  0
 21 15  1  0  0  0  0
 21 18  2  0  0  0  0
 22 19  2  0  0  0  0
 22 20  1  0  0  0  0
 23 18  1  0  0  0  0
 24 19  1  0  0  0  0
 25 19  1  0  0  0  0
 27  1  1  0  0  0  0
 27  2  1  0  0  0  0
 27  3  1  0  0  0  0
 28 12  1  0  0  0  0
 28 23  1  0  0  0  0
 28 26  1  0  0  0  0
 29 14  1  0  0  0  0
 29 24  1  0  0  0  0
 29 26  1  0  0  0  0
 30 25  2  0  0  0  0
 31 11  1  0  0  0  0
 31 27  1  0  0  0  0
 32 15  1  4  0  0  0
 32 17  2  0  0  0  0
 33  4  1  0  0  0  0
 33  5  1  0  0  0  0
 33 16  1  0  0  0  0
 34  6  1  0  0  0  0
 34  7  1  0  0  0  0
 20 34  1  1  0  0  0
 35 17  1  0  0  0  0
 36 21  1  0  0  0  0
 37 22  1  0  0  0  0
 38 23  2  0  0  0  0
 39 24  2  0  0  0  0
 40 25  1  0  0  0  0
 41 26  2  0  0  0  0
 28 42  1  1  0  0  0
 29 43  1  1  0  0  0
 12 44  1  1  0  0  0
 14 45  1  1  0  0  0
 20 46  1  6  0  0  0
M  CHG  1  30   1
M  END
> <DATABASE_ID>
MMDBc0055155

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@@]12CC3=C(C=C(N=C(O)CNC(C)(C)C)C(O)=C3C(=O)[C@]1(O)C(=O)[C@]1(O)C(=O)C(C(O)=[NH2+])=C(O)[C@@]([H])(N(C)C)[C@]1([H])C2)N(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C29H39N5O9/c1-27(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-20(34(6)7)22(37)19(25(30)40)24(39)29(14,43)26(41)28(12,42)23(38)18(13)21(15)36/h10,12,14,20,31,36-37,42-43H,8-9,11H2,1-7H3,(H2,30,40)(H,32,35)/p+1/t12-,14-,20-,28-,29+/m0/s1

> <INCHI_KEY>
RKNGHEJZSVXSDR-GAABGNNBSA-O

> <FORMULA>
C29H40N5O9

> <MOLECULAR_WEIGHT>
602.664

> <EXACT_MASS>
602.282054308

> <JCHEM_ACCEPTOR_COUNT>
13

> <JCHEM_ATOM_COUNT>
83

> <JCHEM_AVERAGE_POLARIZABILITY>
62.64010473687626

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
1

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
{[(4S,4aS,5aR,11aS,12aR)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracen-2-yl](hydroxy)methylidene}azanium

> <JCHEM_LOGP>
-5.63991541693168

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA>
1.4206762458851223

> <JCHEM_PKA_STRONGEST_ACIDIC>
-2.9002974762706764

> <JCHEM_PKA_STRONGEST_BASIC>
13.815270851425272

> <JCHEM_POLAR_SURFACE_AREA>
229.04999999999995

> <JCHEM_REFRACTIVITY>
171.13460000000006

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
{[(4S,4aS,5aR,11aS,12aR)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-4a,5,5a,6-tetrahydro-4H-tetracen-2-yl](hydroxy)methylidene}azanium

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-JUN-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-JUN-22         0                                  
HETATM    1  C   UNK     0      16.004  -6.160   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      15.440  -4.056   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      13.900  -6.724   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       8.002   4.620   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      10.669   4.620   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -0.000   4.620   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       2.667   4.620   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      10.669   1.540   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      13.337  -3.080   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       8.002   1.540   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      10.669  -0.000   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.336   2.310   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      12.003  -2.310   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       8.002   0.000   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.000  -0.000   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -0.000   1.540   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      14.670  -5.390   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   30  N   UNK     0      -1.334  -2.310   0.000  0.00  0.00           N+1
HETATM   31  N   UNK     0      13.337  -4.620   0.000  0.00  0.00           N+0
HETATM   32  N   UNK     0      12.003  -0.770   0.000  0.00  0.00           N+0
HETATM   33  N   UNK     0       9.336   3.850   0.000  0.00  0.00           N+0
HETATM   34  N   UNK     0       1.334   3.850   0.000  0.00  0.00           N+0
HETATM   35  O   UNK     0      10.669  -3.080   0.000  0.00  0.00           O+0
HETATM   36  O   UNK     0       9.336  -2.310   0.000  0.00  0.00           O+0
HETATM   37  O   UNK     0      -1.334   2.310   0.000  0.00  0.00           O+0
HETATM   38  O   UNK     0       6.668  -2.310   0.000  0.00  0.00           O+0
HETATM   39  O   UNK     0       1.334  -2.310   0.000  0.00  0.00           O+0
HETATM   40  O   UNK     0      -2.667  -0.000   0.000  0.00  0.00           O+0
HETATM   41  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
HETATM   42  O   UNK     0       5.335  -1.540   0.000  0.00  0.00           O+0
HETATM   43  O   UNK     0       2.667  -1.540   0.000  0.00  0.00           O+0
HETATM   44  H   UNK     0       4.001   0.770   0.000  0.00  0.00           H+0
HETATM   45  H   UNK     0       1.334   0.770   0.000  0.00  0.00           H+0
HETATM   46  H   UNK     0      -0.000   3.080   0.000  0.00  0.00           H+0
CONECT    1   27                                                            
CONECT    2   27                                                            
CONECT    3   27                                                            
CONECT    4   33                                                            
CONECT    5   33                                                            
CONECT    6   34                                                            
CONECT    7   34                                                            
CONECT    8   12   13                                                       
CONECT    9   12   14                                                       
CONECT   10   15   16                                                       
CONECT   11   17   31                                                       
CONECT   12    8    9   28   44                                             
CONECT   13    8   16   18                                                  
CONECT   14    9   20   29   45                                             
CONECT   15   10   21   32                                                  
CONECT   16   10   13   33                                                  
CONECT   17   11   32   35                                                  
CONECT   18   13   21   23                                                  
CONECT   19   22   24   25                                                  
CONECT   20   14   22   34   46                                             
CONECT   21   15   18   36                                                  
CONECT   22   19   20   37                                                  
CONECT   23   18   28   38                                                  
CONECT   24   19   29   39                                                  
CONECT   25   19   30   40                                                  
CONECT   26   28   29   41                                                  
CONECT   27    1    2    3   31                                             
CONECT   28   12   23   26   42                                             
CONECT   29   14   24   26   43                                             
CONECT   30   25                                                            
CONECT   31   11   27                                                       
CONECT   32   15   17                                                       
CONECT   33    4    5   16                                                  
CONECT   34    6    7   20                                                  
CONECT   35   17                                                            
CONECT   36   21                                                            
CONECT   37   22                                                            
CONECT   38   23                                                            
CONECT   39   24                                                            
CONECT   40   25                                                            
CONECT   41   26                                                            
CONECT   42   28                                                            
CONECT   43   29                                                            
CONECT   44   12                                                            
CONECT   45   14                                                            
CONECT   46   20                                                            
MASTER        0    0    0    0    0    0    0    0   46    0   98    0
END

Synonyms

Not Available

Molecular Formula

C₂₉H₄₀N₅O₉

Average Mass

602.664

Monoisotopic Mass

602.282054308

IUPAC Name

{[(4S,4aS,5aR,11aS,12aR)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracen-2-yl](hydroxy)methylidene}azanium

Traditional Name

{[(4S,4aS,5aR,11aS,12aR)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-4a,5,5a,6-tetrahydro-4H-tetracen-2-yl](hydroxy)methylidene}azanium

CAS Registry Number

Not Available

SMILES

[H][C@@]12CC3=C(C=C(N=C(O)CNC(C)(C)C)C(O)=C3C(=O)[C@]1(O)C(=O)[C@]1(O)C(=O)C(C(O)=[NH2+])=C(O)[C@@]([H])(N(C)C)[C@]1([H])C2)N(C)C

InChI Identifier

InChI=1S/C29H39N5O9/c1-27(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-20(34(6)7)22(37)19(25(30)40)24(39)29(14,43)26(41)28(12,42)23(38)18(13)21(15)36/h10,12,14,20,31,36-37,42-43H,8-9,11H2,1-7H3,(H2,30,40)(H,32,35)/p+1/t12-,14-,20-,28-,29+/m0/s1

InChI Key

RKNGHEJZSVXSDR-GAABGNNBSA-O

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as tetracyclines. These are polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Tetracyclines

Sub Class

Not Available

Direct Parent

Tetracyclines

Alternative Parents

Substituents

Tetracycline
Tetralin
Dialkylarylamine
Aryl alkyl ketone
Aryl ketone
Tertiary aliphatic/aromatic amine
Cyclohexenone
Aralkylamine
Benzenoid
Vinylogous acid
Tertiary alcohol
Cyclic alcohol
Tertiary aliphatic amine
Tertiary amine
Ketone
Secondary amine
Polyol
Enol
Secondary aliphatic amine
Carboximidic acid derivative
Carboximidic acid
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Carbonyl group
Amine
Alcohol
Organic cation
Aromatic homopolycyclic compound

Molecular Framework

Aromatic homopolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
logP	-5.6	ChemAxon
pKa (Strongest Acidic)	-2.9	ChemAxon
pKa (Strongest Basic)	13.82	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	13	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	229.05 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	171.13 m³·mol⁻¹	ChemAxon
Polarizability	62.64 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (eluted)	2025-10-24	485.1
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (eluted)	2025-10-24	292.9
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-24	139.4
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-24	367.3
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-24	283.7
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (eluted)	2025-10-24	164.5
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	863.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-24	825.4
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-24	244.8
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	153.8
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-24	442.4
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	155.7
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	115.1
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (void)	2025-10-24	187.8
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	328.1
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	73.5
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	230.8
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-24	993.4
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-24	674.1

Retention Indices

Chromatography Type	Peak Label	SMILES	Stationary Phase	Deposition Date	Retention Index
Gas Chromatography	11a-hydroxytigecycline_TMS_1	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2576.55
Gas Chromatography	11a-hydroxytigecycline_TMS_2	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1567.89
Gas Chromatography	11a-hydroxytigecycline_TMS_3	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2009.96
Gas Chromatography	11a-hydroxytigecycline_TMS_4	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1199.26
Gas Chromatography	11a-hydroxytigecycline_TMS_5	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3444.72
Gas Chromatography	11a-hydroxytigecycline_TMS_6	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1023.52
Gas Chromatography	11a-hydroxytigecycline_TMS_7	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	168.058
Gas Chromatography	11a-hydroxytigecycline_TMS_8	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	785.403
Gas Chromatography	11a-hydroxytigecycline_TMS_9	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1325.0
Gas Chromatography	11a-hydroxytigecycline_TMS_10	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2672.1
Gas Chromatography	11a-hydroxytigecycline_TMS_11	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1821.23
Gas Chromatography	11a-hydroxytigecycline_TMS_12	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1196.88
Gas Chromatography	11a-hydroxytigecycline_TMS_13	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1830.35
Gas Chromatography	11a-hydroxytigecycline_TMS_14	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2720.44
Gas Chromatography	11a-hydroxytigecycline_TMS_15	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1317.01
Gas Chromatography	11a-hydroxytigecycline_TMS_16	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1985.22
Gas Chromatography	11a-hydroxytigecycline_TMS_17	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2806.41
Gas Chromatography	11a-hydroxytigecycline_TMS_18	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3874.45
Gas Chromatography	11a-hydroxytigecycline_TMS_19	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2554.2
Gas Chromatography	11a-hydroxytigecycline_TMS_20	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1364.0
Gas Chromatography	11a-hydroxytigecycline_TMS_21	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2886.49
Gas Chromatography	11a-hydroxytigecycline_TMS_22	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2819.47
Gas Chromatography	11a-hydroxytigecycline_TMS_23	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3619.22
Gas Chromatography	11a-hydroxytigecycline_TMS_24	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1933.0
Gas Chromatography	11a-hydroxytigecycline_TMS_25	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2220.56
Gas Chromatography	11a-hydroxytigecycline_TMS_26	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3570.04
Gas Chromatography	11a-hydroxytigecycline_TMS_27	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	702.248
Gas Chromatography	11a-hydroxytigecycline_TMS_28	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	356.172
Gas Chromatography	11a-hydroxytigecycline_TMS_29	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1036.45
Gas Chromatography	11a-hydroxytigecycline_TMS_30	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1690.33
Gas Chromatography	11a-hydroxytigecycline_TMS_31	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2100.54
Gas Chromatography	11a-hydroxytigecycline_TMS_32	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1376.86
Gas Chromatography	11a-hydroxytigecycline_TMS_33	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2769.2
Gas Chromatography	11a-hydroxytigecycline_TMS_34	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	851.312
Gas Chromatography	11a-hydroxytigecycline_TMS_35	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1998.35
Gas Chromatography	11a-hydroxytigecycline_TMS_36	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2611.56
Gas Chromatography	11a-hydroxytigecycline_TMS_37	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2221.1
Gas Chromatography	11a-hydroxytigecycline_TMS_38	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2379.39
Gas Chromatography	11a-hydroxytigecycline_TMS_39	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3764.08
Gas Chromatography	11a-hydroxytigecycline_TMS_40	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	264.649
Gas Chromatography	11a-hydroxytigecycline_TMS_41	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1496.06
Gas Chromatography	11a-hydroxytigecycline_TMS_42	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2974.28
Gas Chromatography	11a-hydroxytigecycline_TMS_43	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1295.77
Gas Chromatography	11a-hydroxytigecycline_TMS_44	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1251.38
Gas Chromatography	11a-hydroxytigecycline_TMS_45	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2857.76
Gas Chromatography	11a-hydroxytigecycline_TMS_46	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3034.06
Gas Chromatography	11a-hydroxytigecycline_TMS_47	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2735.36
Gas Chromatography	11a-hydroxytigecycline_TMS_48	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2006.43
Gas Chromatography	11a-hydroxytigecycline_TMS_49	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	662.661
Gas Chromatography	11a-hydroxytigecycline_TMS_50	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2567.15
Gas Chromatography	11a-hydroxytigecycline_TMS_51	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3781.05
Gas Chromatography	11a-hydroxytigecycline_TMS_52	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1449.03
Gas Chromatography	11a-hydroxytigecycline_TMS_53	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	563.995
Gas Chromatography	11a-hydroxytigecycline_TMS_54	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	843.784
Gas Chromatography	11a-hydroxytigecycline_TMS_55	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1697.45
Gas Chromatography	11a-hydroxytigecycline_TMS_56	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1780.48
Gas Chromatography	11a-hydroxytigecycline_TMS_57	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1604.11
Gas Chromatography	11a-hydroxytigecycline_TMS_58	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1357.23
Gas Chromatography	11a-hydroxytigecycline_TMS_59	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2370.79
Gas Chromatography	11a-hydroxytigecycline_TMS_60	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2125.24
Gas Chromatography	11a-hydroxytigecycline_TMS_61	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2231.5
Gas Chromatography	11a-hydroxytigecycline_TMS_62	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	801.833
Gas Chromatography	11a-hydroxytigecycline_TMS_63	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1823.34
Gas Chromatography	11a-hydroxytigecycline_TMS_64	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2289.17
Gas Chromatography	11a-hydroxytigecycline_TMS_65	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1321.32
Gas Chromatography	11a-hydroxytigecycline_TMS_66	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3159.37
Gas Chromatography	11a-hydroxytigecycline_TMS_67	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1636.51
Gas Chromatography	11a-hydroxytigecycline_TMS_68	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2598.91
Gas Chromatography	11a-hydroxytigecycline_TMS_69	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2092.26
Gas Chromatography	11a-hydroxytigecycline_TMS_70	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1613.88
Gas Chromatography	11a-hydroxytigecycline_TMS_71	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3115.83
Gas Chromatography	11a-hydroxytigecycline_TMS_72	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1329.77
Gas Chromatography	11a-hydroxytigecycline_TMS_73	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2794.2
Gas Chromatography	11a-hydroxytigecycline_TMS_74	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3882.43
Gas Chromatography	11a-hydroxytigecycline_TMS_75	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2402.65
Gas Chromatography	11a-hydroxytigecycline_TMS_76	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	708.233
Gas Chromatography	11a-hydroxytigecycline_TMS_77	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2504.62
Gas Chromatography	11a-hydroxytigecycline_TMS_78	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1217.66
Gas Chromatography	11a-hydroxytigecycline_TMS_79	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1448.05
Gas Chromatography	11a-hydroxytigecycline_TMS_80	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2333.78
Gas Chromatography	11a-hydroxytigecycline_TMS_81	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1887.05
Gas Chromatography	11a-hydroxytigecycline_TMS_82	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	216.445
Gas Chromatography	11a-hydroxytigecycline_TMS_83	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2028.96
Gas Chromatography	11a-hydroxytigecycline_TMS_84	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2501.95
Gas Chromatography	11a-hydroxytigecycline_TMS_85	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2360.86
Gas Chromatography	11a-hydroxytigecycline_TMS_86	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1570.09
Gas Chromatography	11a-hydroxytigecycline_TMS_87	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1213.4
Gas Chromatography	11a-hydroxytigecycline_TMS_88	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3255.06
Gas Chromatography	11a-hydroxytigecycline_TMS_89	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	995.038
Gas Chromatography	11a-hydroxytigecycline_TMS_90	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1955.42
Gas Chromatography	11a-hydroxytigecycline_TMS_91	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2813.35
Gas Chromatography	11a-hydroxytigecycline_TMS_92	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3638.04
Gas Chromatography	11a-hydroxytigecycline_TMS_93	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1947.2
Gas Chromatography	11a-hydroxytigecycline_TMS_94	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2224.13
Gas Chromatography	11a-hydroxytigecycline_TMS_95	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1501.3
Gas Chromatography	11a-hydroxytigecycline_TMS_96	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3376.79
Gas Chromatography	11a-hydroxytigecycline_TMS_97	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2480.16
Gas Chromatography	11a-hydroxytigecycline_TMS_98	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2247.97
Gas Chromatography	11a-hydroxytigecycline_TMS_99	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1513.52
Gas Chromatography	11a-hydroxytigecycline_TMS_100	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2161.55
Gas Chromatography	11a-hydroxytigecycline_TMS_101	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1584.37
Gas Chromatography	11a-hydroxytigecycline_TMS_102	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2688.38
Gas Chromatography	11a-hydroxytigecycline_TMS_103	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	709.919
Gas Chromatography	11a-hydroxytigecycline_TMS_104	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	-401.952
Gas Chromatography	11a-hydroxytigecycline_TMS_105	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1769.03
Gas Chromatography	11a-hydroxytigecycline_TMS_106	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1717.73
Gas Chromatography	11a-hydroxytigecycline_TMS_107	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2014.11
Gas Chromatography	11a-hydroxytigecycline_TMS_108	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2707.59
Gas Chromatography	11a-hydroxytigecycline_TMS_109	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2242.57
Gas Chromatography	11a-hydroxytigecycline_TMS_110	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	894.081
Gas Chromatography	11a-hydroxytigecycline_TMS_111	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2170.08
Gas Chromatography	11a-hydroxytigecycline_TMS_112	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1496.06
Gas Chromatography	11a-hydroxytigecycline_TMS_113	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1556.85
Gas Chromatography	11a-hydroxytigecycline_TMS_114	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	51.4208
Gas Chromatography	11a-hydroxytigecycline_TMS_115	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2761.34
Gas Chromatography	11a-hydroxytigecycline_TMS_116	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2270.08
Gas Chromatography	11a-hydroxytigecycline_TMS_117	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1070.75
Gas Chromatography	11a-hydroxytigecycline_TMS_118	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1246.22
Gas Chromatography	11a-hydroxytigecycline_TMS_119	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	169.036
Gas Chromatography	11a-hydroxytigecycline_TMS_120	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1464.18
Gas Chromatography	11a-hydroxytigecycline_TMS_121	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2404.07
Gas Chromatography	11a-hydroxytigecycline_TMS_122	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	831.144
Gas Chromatography	11a-hydroxytigecycline_TMS_123	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2359.18
Gas Chromatography	11a-hydroxytigecycline_TMS_124	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1003.97
Gas Chromatography	11a-hydroxytigecycline_TMS_125	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3310.02
Gas Chromatography	11a-hydroxytigecycline_TMS_126	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2026.16
Gas Chromatography	11a-hydroxytigecycline_TMS_127	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1420.4
Gas Chromatography	11a-hydroxytigecycline_TMS_128	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1313.42
Gas Chromatography	11a-hydroxytigecycline_TMS_129	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1319.97
Gas Chromatography	11a-hydroxytigecycline_TMS_130	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2748.96
Gas Chromatography	11a-hydroxytigecycline_TMS_131	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3294.4
Gas Chromatography	11a-hydroxytigecycline_TMS_132	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2139.78
Gas Chromatography	11a-hydroxytigecycline_TMS_133	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	647.801
Gas Chromatography	11a-hydroxytigecycline_TMS_134	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3134.3
Gas Chromatography	11a-hydroxytigecycline_TMS_135	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1153.07
Gas Chromatography	11a-hydroxytigecycline_TMS_136	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	522.118
Gas Chromatography	11a-hydroxytigecycline_TMS_137	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	835.391
Gas Chromatography	11a-hydroxytigecycline_TMS_138	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2288.28
Gas Chromatography	11a-hydroxytigecycline_TMS_139	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1916.62
Gas Chromatography	11a-hydroxytigecycline_TMS_140	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2094.65
Gas Chromatography	11a-hydroxytigecycline_TMS_141	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2212.84
Gas Chromatography	11a-hydroxytigecycline_TMS_142	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2543.03
Gas Chromatography	11a-hydroxytigecycline_TMS_143	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2511.82
Gas Chromatography	11a-hydroxytigecycline_TMS_144	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1265.53
Gas Chromatography	11a-hydroxytigecycline_TMS_145	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1826.44
Gas Chromatography	11a-hydroxytigecycline_TMS_146	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1812.57
Gas Chromatography	11a-hydroxytigecycline_TMS_147	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2665.45
Gas Chromatography	11a-hydroxytigecycline_TMS_148	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1893.59
Gas Chromatography	11a-hydroxytigecycline_TMS_149	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1273.41
Gas Chromatography	11a-hydroxytigecycline_TMS_150	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2251.51
Gas Chromatography	11a-hydroxytigecycline_TMS_151	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	960.693
Gas Chromatography	11a-hydroxytigecycline_TMS_152	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1132.3
Gas Chromatography	11a-hydroxytigecycline_TMS_153	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1860.06
Gas Chromatography	11a-hydroxytigecycline_TMS_154	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2332.61
Gas Chromatography	11a-hydroxytigecycline_TMS_155	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2004.07
Gas Chromatography	11a-hydroxytigecycline_TMS_156	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	289.171
Gas Chromatography	11a-hydroxytigecycline_TMS_157	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	684.94
Gas Chromatography	11a-hydroxytigecycline_TMS_158	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1095.19
Gas Chromatography	11a-hydroxytigecycline_TMS_159	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1872.87
Gas Chromatography	11a-hydroxytigecycline_TMS_160	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	984.301
Gas Chromatography	11a-hydroxytigecycline_TMS_161	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1716.21
Gas Chromatography	11a-hydroxytigecycline_TMS_162	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1392.49
Gas Chromatography	11a-hydroxytigecycline_TMS_163	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2426.98
Gas Chromatography	11a-hydroxytigecycline_TMS_164	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3435.9
Gas Chromatography	11a-hydroxytigecycline_TMS_165	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3180.11
Gas Chromatography	11a-hydroxytigecycline_TMS_166	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2408.84
Gas Chromatography	11a-hydroxytigecycline_TMS_167	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1399.91
Gas Chromatography	11a-hydroxytigecycline_TMS_168	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1335.21
Gas Chromatography	11a-hydroxytigecycline_TMS_169	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	893.619
Gas Chromatography	11a-hydroxytigecycline_TMS_170	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3058.59
Gas Chromatography	11a-hydroxytigecycline_TMS_171	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2010.18
Gas Chromatography	11a-hydroxytigecycline_TMS_172	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2649.34
Gas Chromatography	11a-hydroxytigecycline_TMS_173	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1787.8
Gas Chromatography	11a-hydroxytigecycline_TMS_174	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2496.26
Gas Chromatography	11a-hydroxytigecycline_TMS_175	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1191.3
Gas Chromatography	11a-hydroxytigecycline_TMS_176	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1823.23
Gas Chromatography	11a-hydroxytigecycline_TMS_177	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2089.31
Gas Chromatography	11a-hydroxytigecycline_TMS_178	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	3096.44
Gas Chromatography	11a-hydroxytigecycline_TMS_179	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	2002.84
Gas Chromatography	11a-hydroxytigecycline_TMS_180	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard non polar	2025-10-24	1797.48
Gas Chromatography	11a-hydroxytigecycline_TMS_181	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2266.3
Gas Chromatography	11a-hydroxytigecycline_TMS_182	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3333.7
Gas Chromatography	11a-hydroxytigecycline_TMS_183	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1323.85
Gas Chromatography	11a-hydroxytigecycline_TMS_184	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2905.2
Gas Chromatography	11a-hydroxytigecycline_TMS_185	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1727.65
Gas Chromatography	11a-hydroxytigecycline_TMS_186	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3806.25
Gas Chromatography	11a-hydroxytigecycline_TMS_187	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	1715.74
Gas Chromatography	11a-hydroxytigecycline_TMS_188	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2625.09
Gas Chromatography	11a-hydroxytigecycline_TMS_189	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	2043.89
Gas Chromatography	11a-hydroxytigecycline_TMS_190	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	3191.21
Gas Chromatography	11a-hydroxytigecycline_TMS_191	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard non polar	2025-10-24	4428.56
Gas Chromatography	11a-hydroxytigecycline_TMS_1	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2656.06
Gas Chromatography	11a-hydroxytigecycline_TMS_2	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2988.45
Gas Chromatography	11a-hydroxytigecycline_TMS_3	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2469.43
Gas Chromatography	11a-hydroxytigecycline_TMS_4	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2059.54
Gas Chromatography	11a-hydroxytigecycline_TMS_5	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2775.16
Gas Chromatography	11a-hydroxytigecycline_TMS_6	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1225.11
Gas Chromatography	11a-hydroxytigecycline_TMS_7	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	791.494
Gas Chromatography	11a-hydroxytigecycline_TMS_8	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3131.87
Gas Chromatography	11a-hydroxytigecycline_TMS_9	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2582.49
Gas Chromatography	11a-hydroxytigecycline_TMS_10	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1954.62
Gas Chromatography	11a-hydroxytigecycline_TMS_11	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1590.99
Gas Chromatography	11a-hydroxytigecycline_TMS_12	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	724.379
Gas Chromatography	11a-hydroxytigecycline_TMS_13	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2529.49
Gas Chromatography	11a-hydroxytigecycline_TMS_14	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2521.34
Gas Chromatography	11a-hydroxytigecycline_TMS_15	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1914.01
Gas Chromatography	11a-hydroxytigecycline_TMS_16	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2911.83
Gas Chromatography	11a-hydroxytigecycline_TMS_17	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2269.71
Gas Chromatography	11a-hydroxytigecycline_TMS_18	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1737.37
Gas Chromatography	11a-hydroxytigecycline_TMS_19	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2462.03
Gas Chromatography	11a-hydroxytigecycline_TMS_20	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3830.38
Gas Chromatography	11a-hydroxytigecycline_TMS_21	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2342.01
Gas Chromatography	11a-hydroxytigecycline_TMS_22	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2488.51
Gas Chromatography	11a-hydroxytigecycline_TMS_23	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2820.49
Gas Chromatography	11a-hydroxytigecycline_TMS_24	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1974.01
Gas Chromatography	11a-hydroxytigecycline_TMS_25	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2931.83
Gas Chromatography	11a-hydroxytigecycline_TMS_26	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3826.63
Gas Chromatography	11a-hydroxytigecycline_TMS_27	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1621.85
Gas Chromatography	11a-hydroxytigecycline_TMS_28	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3463.33
Gas Chromatography	11a-hydroxytigecycline_TMS_29	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2154.84
Gas Chromatography	11a-hydroxytigecycline_TMS_30	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3024.76
Gas Chromatography	11a-hydroxytigecycline_TMS_31	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2285.16
Gas Chromatography	11a-hydroxytigecycline_TMS_32	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	468.984
Gas Chromatography	11a-hydroxytigecycline_TMS_33	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	368.519
Gas Chromatography	11a-hydroxytigecycline_TMS_34	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	4303.81
Gas Chromatography	11a-hydroxytigecycline_TMS_35	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1912.08
Gas Chromatography	11a-hydroxytigecycline_TMS_36	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1692.87
Gas Chromatography	11a-hydroxytigecycline_TMS_37	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2520.12
Gas Chromatography	11a-hydroxytigecycline_TMS_38	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2980.54
Gas Chromatography	11a-hydroxytigecycline_TMS_39	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	655.656
Gas Chromatography	11a-hydroxytigecycline_TMS_40	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2097.6
Gas Chromatography	11a-hydroxytigecycline_TMS_41	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1181.41
Gas Chromatography	11a-hydroxytigecycline_TMS_42	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3089.27
Gas Chromatography	11a-hydroxytigecycline_TMS_43	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2527.74
Gas Chromatography	11a-hydroxytigecycline_TMS_44	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1561.36
Gas Chromatography	11a-hydroxytigecycline_TMS_45	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1446.36
Gas Chromatography	11a-hydroxytigecycline_TMS_46	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2695.17
Gas Chromatography	11a-hydroxytigecycline_TMS_47	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2730.27
Gas Chromatography	11a-hydroxytigecycline_TMS_48	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2148.43
Gas Chromatography	11a-hydroxytigecycline_TMS_49	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1824.56
Gas Chromatography	11a-hydroxytigecycline_TMS_50	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2003.79
Gas Chromatography	11a-hydroxytigecycline_TMS_51	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3813.11
Gas Chromatography	11a-hydroxytigecycline_TMS_52	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2324.93
Gas Chromatography	11a-hydroxytigecycline_TMS_53	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2192.04
Gas Chromatography	11a-hydroxytigecycline_TMS_54	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2695.76
Gas Chromatography	11a-hydroxytigecycline_TMS_55	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1464.92
Gas Chromatography	11a-hydroxytigecycline_TMS_56	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2764.22
Gas Chromatography	11a-hydroxytigecycline_TMS_57	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2548.84
Gas Chromatography	11a-hydroxytigecycline_TMS_58	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2274.53
Gas Chromatography	11a-hydroxytigecycline_TMS_59	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2456.73
Gas Chromatography	11a-hydroxytigecycline_TMS_60	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1830.0
Gas Chromatography	11a-hydroxytigecycline_TMS_61	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1400.6
Gas Chromatography	11a-hydroxytigecycline_TMS_62	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1901.07
Gas Chromatography	11a-hydroxytigecycline_TMS_63	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1481.13
Gas Chromatography	11a-hydroxytigecycline_TMS_64	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3316.76
Gas Chromatography	11a-hydroxytigecycline_TMS_65	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1807.75
Gas Chromatography	11a-hydroxytigecycline_TMS_66	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	446.489
Gas Chromatography	11a-hydroxytigecycline_TMS_67	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2147.55
Gas Chromatography	11a-hydroxytigecycline_TMS_68	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1995.11
Gas Chromatography	11a-hydroxytigecycline_TMS_69	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2743.61
Gas Chromatography	11a-hydroxytigecycline_TMS_70	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	486.618
Gas Chromatography	11a-hydroxytigecycline_TMS_71	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2355.99
Gas Chromatography	11a-hydroxytigecycline_TMS_72	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2811.39
Gas Chromatography	11a-hydroxytigecycline_TMS_73	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1956.3
Gas Chromatography	11a-hydroxytigecycline_TMS_74	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2095.4
Gas Chromatography	11a-hydroxytigecycline_TMS_75	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1017.04
Gas Chromatography	11a-hydroxytigecycline_TMS_76	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2434.81
Gas Chromatography	11a-hydroxytigecycline_TMS_77	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3730.58
Gas Chromatography	11a-hydroxytigecycline_TMS_78	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3021.19
Gas Chromatography	11a-hydroxytigecycline_TMS_79	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2773.68
Gas Chromatography	11a-hydroxytigecycline_TMS_80	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1927.99
Gas Chromatography	11a-hydroxytigecycline_TMS_81	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	866.995
Gas Chromatography	11a-hydroxytigecycline_TMS_82	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	699.08
Gas Chromatography	11a-hydroxytigecycline_TMS_83	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1261.15
Gas Chromatography	11a-hydroxytigecycline_TMS_84	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2512.03
Gas Chromatography	11a-hydroxytigecycline_TMS_85	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1103.93
Gas Chromatography	11a-hydroxytigecycline_TMS_86	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	879.274
Gas Chromatography	11a-hydroxytigecycline_TMS_87	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3985.57
Gas Chromatography	11a-hydroxytigecycline_TMS_88	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1876.56
Gas Chromatography	11a-hydroxytigecycline_TMS_89	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1420.33
Gas Chromatography	11a-hydroxytigecycline_TMS_90	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	929.802
Gas Chromatography	11a-hydroxytigecycline_TMS_91	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1919.93
Gas Chromatography	11a-hydroxytigecycline_TMS_92	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2632.24
Gas Chromatography	11a-hydroxytigecycline_TMS_93	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1584.67
Gas Chromatography	11a-hydroxytigecycline_TMS_94	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3399.33
Gas Chromatography	11a-hydroxytigecycline_TMS_95	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1495.37
Gas Chromatography	11a-hydroxytigecycline_TMS_96	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	4084.7
Gas Chromatography	11a-hydroxytigecycline_TMS_97	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1443.62
Gas Chromatography	11a-hydroxytigecycline_TMS_98	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1687.7
Gas Chromatography	11a-hydroxytigecycline_TMS_99	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2585.63
Gas Chromatography	11a-hydroxytigecycline_TMS_100	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1780.72
Gas Chromatography	11a-hydroxytigecycline_TMS_101	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1482.07
Gas Chromatography	11a-hydroxytigecycline_TMS_102	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	130.046
Gas Chromatography	11a-hydroxytigecycline_TMS_103	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2171.63
Gas Chromatography	11a-hydroxytigecycline_TMS_104	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	634.396
Gas Chromatography	11a-hydroxytigecycline_TMS_105	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	4788.1
Gas Chromatography	11a-hydroxytigecycline_TMS_106	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2505.19
Gas Chromatography	11a-hydroxytigecycline_TMS_107	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3805.81
Gas Chromatography	11a-hydroxytigecycline_TMS_108	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2394.85
Gas Chromatography	11a-hydroxytigecycline_TMS_109	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	680.486
Gas Chromatography	11a-hydroxytigecycline_TMS_110	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1207.21
Gas Chromatography	11a-hydroxytigecycline_TMS_111	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1085.46
Gas Chromatography	11a-hydroxytigecycline_TMS_112	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	625.163
Gas Chromatography	11a-hydroxytigecycline_TMS_113	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2829.79
Gas Chromatography	11a-hydroxytigecycline_TMS_114	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2263.57
Gas Chromatography	11a-hydroxytigecycline_TMS_115	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1924.37
Gas Chromatography	11a-hydroxytigecycline_TMS_116	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1145.42
Gas Chromatography	11a-hydroxytigecycline_TMS_117	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	583.441
Gas Chromatography	11a-hydroxytigecycline_TMS_118	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1463.84
Gas Chromatography	11a-hydroxytigecycline_TMS_119	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2394.51
Gas Chromatography	11a-hydroxytigecycline_TMS_120	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	797.747
Gas Chromatography	11a-hydroxytigecycline_TMS_121	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1575.58
Gas Chromatography	11a-hydroxytigecycline_TMS_122	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2345.92
Gas Chromatography	11a-hydroxytigecycline_TMS_123	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1617.38
Gas Chromatography	11a-hydroxytigecycline_TMS_124	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2109.39
Gas Chromatography	11a-hydroxytigecycline_TMS_125	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	925.97
Gas Chromatography	11a-hydroxytigecycline_TMS_126	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2383.62
Gas Chromatography	11a-hydroxytigecycline_TMS_127	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	710.683
Gas Chromatography	11a-hydroxytigecycline_TMS_128	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1245.68
Gas Chromatography	11a-hydroxytigecycline_TMS_129	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2058.95
Gas Chromatography	11a-hydroxytigecycline_TMS_130	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	292.595
Gas Chromatography	11a-hydroxytigecycline_TMS_131	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3810.91
Gas Chromatography	11a-hydroxytigecycline_TMS_132	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3873.75
Gas Chromatography	11a-hydroxytigecycline_TMS_133	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1515.07
Gas Chromatography	11a-hydroxytigecycline_TMS_134	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1483.91
Gas Chromatography	11a-hydroxytigecycline_TMS_135	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3405.28
Gas Chromatography	11a-hydroxytigecycline_TMS_136	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	935.684
Gas Chromatography	11a-hydroxytigecycline_TMS_137	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3251.37
Gas Chromatography	11a-hydroxytigecycline_TMS_138	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3149.58
Gas Chromatography	11a-hydroxytigecycline_TMS_139	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3039.79
Gas Chromatography	11a-hydroxytigecycline_TMS_140	CN(C)C1=CC(N=C(CNC(C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2717.58
Gas Chromatography	11a-hydroxytigecycline_TMS_141	CN(C)C1=CC(N=C(CN(C(C)(C)C)[Si](C)(C)C)O[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2240.01
Gas Chromatography	11a-hydroxytigecycline_TMS_142	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2102.68
Gas Chromatography	11a-hydroxytigecycline_TMS_143	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1816.65
Gas Chromatography	11a-hydroxytigecycline_TMS_144	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	873.26
Gas Chromatography	11a-hydroxytigecycline_TMS_145	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1690.95
Gas Chromatography	11a-hydroxytigecycline_TMS_146	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2592.96
Gas Chromatography	11a-hydroxytigecycline_TMS_147	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	781.55
Gas Chromatography	11a-hydroxytigecycline_TMS_148	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2746.18
Gas Chromatography	11a-hydroxytigecycline_TMS_149	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1826.63
Gas Chromatography	11a-hydroxytigecycline_TMS_150	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1950.06
Gas Chromatography	11a-hydroxytigecycline_TMS_151	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3089.06
Gas Chromatography	11a-hydroxytigecycline_TMS_152	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1150.94
Gas Chromatography	11a-hydroxytigecycline_TMS_153	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2992.8
Gas Chromatography	11a-hydroxytigecycline_TMS_154	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2722.23
Gas Chromatography	11a-hydroxytigecycline_TMS_155	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3736.82
Gas Chromatography	11a-hydroxytigecycline_TMS_156	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	20.6767
Gas Chromatography	11a-hydroxytigecycline_TMS_157	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1979.03
Gas Chromatography	11a-hydroxytigecycline_TMS_158	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2138.28
Gas Chromatography	11a-hydroxytigecycline_TMS_159	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1940.58
Gas Chromatography	11a-hydroxytigecycline_TMS_160	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1408.76
Gas Chromatography	11a-hydroxytigecycline_TMS_161	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2716.93
Gas Chromatography	11a-hydroxytigecycline_TMS_162	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1953.16
Gas Chromatography	11a-hydroxytigecycline_TMS_163	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1747.23
Gas Chromatography	11a-hydroxytigecycline_TMS_164	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	280.177
Gas Chromatography	11a-hydroxytigecycline_TMS_165	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1985.93
Gas Chromatography	11a-hydroxytigecycline_TMS_166	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O[Si](C)(C)C)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2847.22
Gas Chromatography	11a-hydroxytigecycline_TMS_167	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3709.14
Gas Chromatography	11a-hydroxytigecycline_TMS_168	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1011.82
Gas Chromatography	11a-hydroxytigecycline_TMS_169	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1589.91
Gas Chromatography	11a-hydroxytigecycline_TMS_170	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2277.58
Gas Chromatography	11a-hydroxytigecycline_TMS_171	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1470.92
Gas Chromatography	11a-hydroxytigecycline_TMS_172	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1088.23
Gas Chromatography	11a-hydroxytigecycline_TMS_173	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3109.12
Gas Chromatography	11a-hydroxytigecycline_TMS_174	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2556.63
Gas Chromatography	11a-hydroxytigecycline_TMS_175	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	2373.44
Gas Chromatography	11a-hydroxytigecycline_TMS_176	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3373.66
Gas Chromatography	11a-hydroxytigecycline_TMS_177	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1793.48
Gas Chromatography	11a-hydroxytigecycline_TMS_178	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1824.68
Gas Chromatography	11a-hydroxytigecycline_TMS_179	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	1600.11
Gas Chromatography	11a-hydroxytigecycline_TMS_180	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O[Si](C)(C)C)C2=O	standard polar	2025-10-24	3830.16
Gas Chromatography	11a-hydroxytigecycline_TMS_181	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3250.68
Gas Chromatography	11a-hydroxytigecycline_TMS_182	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH2+])O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2490.91
Gas Chromatography	11a-hydroxytigecycline_TMS_183	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[NH+][Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	742.994
Gas Chromatography	11a-hydroxytigecycline_TMS_184	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2972.77
Gas Chromatography	11a-hydroxytigecycline_TMS_185	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3935.57
Gas Chromatography	11a-hydroxytigecycline_TMS_186	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	1245.65
Gas Chromatography	11a-hydroxytigecycline_TMS_187	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O[Si](C)(C)C)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	554.676
Gas Chromatography	11a-hydroxytigecycline_TMS_188	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(=[NH+][Si](C)(C)C)O[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	3790.3
Gas Chromatography	11a-hydroxytigecycline_TMS_189	CN(C)C1=CC(N=C(O)CNC(C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	205.303
Gas Chromatography	11a-hydroxytigecycline_TMS_190	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(O[Si](C)(C)C)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	2809.29
Gas Chromatography	11a-hydroxytigecycline_TMS_191	CN(C)C1=CC(N=C(O)CN(C(C)(C)C)[Si](C)(C)C)=C(O)C2=C1C[C@H]1C[C@H]3[C@H](N(C)C)C(O[Si](C)(C)C)=C(C(O)=[N+]([Si](C)(C)C)[Si](C)(C)C)C(=O)[C@@]3(O)C(=O)[C@@]1(O)C2=O	standard polar	2025-10-24	49.1723

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria/Eubacteria	Bacteroidetes	1	Human feces; Human stool; Human saliva

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for 11a-hydroxytigecycline (MMDBc0055155)

MOL for #<Metabolite:0x00007fae00df9cc8>

3D MOL for #<Metabolite:0x00007fae00df9cc8>

3D SDF for #<Metabolite:0x00007fae00df9cc8>

3D-SDF for #<Metabolite:0x00007fae00df9cc8>

PDB for #<Metabolite:0x00007fae00df9cc8>

3D PDB for #<Metabolite:0x00007fae00df9cc8>

SMILES for #<Metabolite:0x00007fae00df9cc8>

INCHI for #<Metabolite:0x00007fae00df9cc8>

Structure for #<Metabolite:0x00007fae00df9cc8>

3D Structure for #<Metabolite:0x00007fae00df9cc8>