MiMeDB: Showing metabocard for 8-methylmenaquinone-6 (MMDBc0055657)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2022-06-17 20:01:25 UTC

Update Date

2025-10-07 16:09:16 UTC

Metabolite ID

MMDBc0055657

Metabolite Identification

Common Name

8-methylmenaquinone-6

Description

8-methylmenaquinone-6 is a member of the vitamin K chemical class, specifically a type of menaquinone. Its chemical structure features a naphthoquinone backbone with a methyl group at the 8-position and a side chain that contributes to its role in electron transport processes. This compound is involved in the electron transport chain, where it participates in redox reactions essential for energy production in various organisms. Specifically, it has been proposed that 8-methylmenaquinone-6, along with menaquinone-6 (MK6), interacts with proteins such as the iron-sulfur protein MccC, the putative quinol dehydrogenase MccD, and the copper chaperone MccL, facilitating electron transfer and contributing to cellular respiration (PMID:30342041 ). The presence of this metabolite underscores its potential importance in bioenergetics and metabolic pathways, highlighting its role in the complex interplay of electron carriers within the cellular milieu.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652306172222012D          

 49 50  0  0  0  0            999 V2000
   12.1460   16.9125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.8605   15.6750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   13.2000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   10.7250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737    8.2500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   14.8500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   12.3750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737    9.9000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    4.9500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   15.6750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.7171   14.4375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   13.2000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   11.9625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   10.7250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592    9.4875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    8.2500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    7.0125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1460   16.0875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.7171   13.6125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   11.1375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592    8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   13.6125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   11.1375    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    8.6625    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    6.1875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    3.7125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
 16 10  1  0  0  0  0
 17 10  1  0  0  0  0
 18 11  1  0  0  0  0
 19 11  1  0  0  0  0
 20 12  1  0  0  0  0
 21 12  1  0  0  0  0
 22 13  1  0  0  0  0
 23 13  1  0  0  0  0
 24 14  1  0  0  0  0
 25 14  1  0  0  0  0
 26 15  2  0  0  0  0
 27 15  1  0  0  0  0
 29 28  1  0  0  0  0
 30  1  1  0  0  0  0
 30  2  1  0  0  0  0
 30 16  2  0  0  0  0
 31  3  1  0  0  0  0
 31 17  1  0  0  0  0
 31 18  2  0  0  0  0
 32  4  1  0  0  0  0
 32 19  1  0  0  0  0
 32 20  2  0  0  0  0
 33  5  1  0  0  0  0
 33 21  1  0  0  0  0
 33 22  2  0  0  0  0
 34  6  1  0  0  0  0
 34 23  1  0  0  0  0
 34 24  2  0  0  0  0
 35  7  1  0  0  0  0
 35 25  1  0  0  0  0
 35 28  2  0  0  0  0
 36  8  1  0  0  0  0
 36 26  1  0  0  0  0
 37  9  1  0  0  0  0
 38 29  1  0  0  0  0
 38 37  2  0  0  0  0
 39 27  2  0  0  0  0
 40 36  2  0  0  0  0
 40 39  1  0  0  0  0
 41 37  1  0  0  0  0
 41 40  1  0  0  0  0
 42 38  1  0  0  0  0
 42 39  1  0  0  0  0
 43 41  2  0  0  0  0
 44 42  2  0  0  0  0
 45 18  1  0  0  0  0
 46 20  1  0  0  0  0
 47 22  1  0  0  0  0
 48 24  1  0  0  0  0
 49 28  1  0  0  0  0
M  END


  Mrv1652306172222012D          

 49 50  0  0  0  0            999 V2000
   12.1460   16.9125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.8605   15.6750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   13.2000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   10.7250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737    8.2500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   14.8500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   12.3750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737    9.9000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    4.9500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   15.6750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.7171   14.4375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   13.2000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   11.9625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   10.7250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592    9.4875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    8.2500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    7.0125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1460   16.0875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.7171   13.6125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   11.1375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592    8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   13.6125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   11.1375    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    8.6625    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    6.1875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    3.7125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
 16 10  1  0  0  0  0
 17 10  1  0  0  0  0
 18 11  1  0  0  0  0
 19 11  1  0  0  0  0
 20 12  1  0  0  0  0
 21 12  1  0  0  0  0
 22 13  1  0  0  0  0
 23 13  1  0  0  0  0
 24 14  1  0  0  0  0
 25 14  1  0  0  0  0
 26 15  2  0  0  0  0
 27 15  1  0  0  0  0
 29 28  1  0  0  0  0
 30  1  1  0  0  0  0
 30  2  1  0  0  0  0
 30 16  2  0  0  0  0
 31  3  1  0  0  0  0
 31 17  1  0  0  0  0
 31 18  2  0  0  0  0
 32  4  1  0  0  0  0
 32 19  1  0  0  0  0
 32 20  2  0  0  0  0
 33  5  1  0  0  0  0
 33 21  1  0  0  0  0
 33 22  2  0  0  0  0
 34  6  1  0  0  0  0
 34 23  1  0  0  0  0
 34 24  2  0  0  0  0
 35  7  1  0  0  0  0
 35 25  1  0  0  0  0
 35 28  2  0  0  0  0
 36  8  1  0  0  0  0
 36 26  1  0  0  0  0
 37  9  1  0  0  0  0
 38 29  1  0  0  0  0
 38 37  2  0  0  0  0
 39 27  2  0  0  0  0
 40 36  2  0  0  0  0
 40 39  1  0  0  0  0
 41 37  1  0  0  0  0
 41 40  1  0  0  0  0
 42 38  1  0  0  0  0
 42 39  1  0  0  0  0
 43 41  2  0  0  0  0
 44 42  2  0  0  0  0
 45 18  1  0  0  0  0
 46 20  1  0  0  0  0
 47 22  1  0  0  0  0
 48 24  1  0  0  0  0
 49 28  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0055657

> <DATABASE_NAME>
MIME

> <SMILES>
[H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=C(C)C=CC=C2C1=O)=C(\C)CCC=C(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C42H58O2/c1-30(2)16-10-17-31(3)18-11-19-32(4)20-12-21-33(5)22-13-23-34(6)24-14-25-35(7)28-29-38-37(9)41(43)40-36(8)26-15-27-39(40)42(38)44/h15-16,18,20,22,24,26-28H,10-14,17,19,21,23,25,29H2,1-9H3/b31-18+,32-20+,33-22+,34-24+,35-28+

> <INCHI_KEY>
HAMLBJAJFRKXHQ-RCIYGOBDSA-N

> <FORMULA>
C42H58O2

> <MOLECULAR_WEIGHT>
594.924

> <EXACT_MASS>
594.443681108

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
102

> <JCHEM_AVERAGE_POLARIZABILITY>
75.86222782997464

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3,5-dimethyl-1,4-dihydronaphthalene-1,4-dione

> <JCHEM_LOGP>
12.312557303666665

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-7.227669134185875

> <JCHEM_POLAR_SURFACE_AREA>
34.14

> <JCHEM_REFRACTIVITY>
198.15320000000006

> <JCHEM_ROTATABLE_BOND_COUNT>
17

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3,5-dimethylnaphthalene-1,4-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-JUN-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-JUN-22         0                                  
HETATM    1  C   UNK     0      22.673  31.570   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      24.006  29.260   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      21.339  24.640   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      18.672  20.020   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      16.004  15.400   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      13.337  10.780   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      10.669   6.160   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       8.002   1.540   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      21.339  27.720   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      18.672  23.100   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      16.004  18.480   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      13.337  13.860   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      10.669   9.240   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.334   3.850   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      21.339  29.260   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      20.005  26.950   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      18.672  24.640   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      17.338  22.330   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      16.004  20.020   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      14.670  17.710   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      13.337  15.400   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      12.003  13.090   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      10.669  10.780   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       9.336   8.470   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       2.667   4.620   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       8.002   6.160   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       8.002   4.620   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      22.673  30.030   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      20.005  25.410   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      17.338  20.790   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      14.670  16.170   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      12.003  11.550   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       9.336   6.930   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       6.668   3.850   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       4.001   3.850   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       5.335   4.620   0.000  0.00  0.00           C+0
HETATM   43  O   UNK     0       5.335   0.000   0.000  0.00  0.00           O+0
HETATM   44  O   UNK     0       5.335   6.160   0.000  0.00  0.00           O+0
HETATM   45  H   UNK     0      17.338  25.410   0.000  0.00  0.00           H+0
HETATM   46  H   UNK     0      14.670  20.790   0.000  0.00  0.00           H+0
HETATM   47  H   UNK     0      12.003  16.170   0.000  0.00  0.00           H+0
HETATM   48  H   UNK     0       9.336  11.550   0.000  0.00  0.00           H+0
HETATM   49  H   UNK     0       6.668   6.930   0.000  0.00  0.00           H+0
CONECT    1   30                                                            
CONECT    2   30                                                            
CONECT    3   31                                                            
CONECT    4   32                                                            
CONECT    5   33                                                            
CONECT    6   34                                                            
CONECT    7   35                                                            
CONECT    8   36                                                            
CONECT    9   37                                                            
CONECT   10   16   17                                                       
CONECT   11   18   19                                                       
CONECT   12   20   21                                                       
CONECT   13   22   23                                                       
CONECT   14   24   25                                                       
CONECT   15   26   27                                                       
CONECT   16   10   30                                                       
CONECT   17   10   31                                                       
CONECT   18   11   31   45                                                  
CONECT   19   11   32                                                       
CONECT   20   12   32   46                                                  
CONECT   21   12   33                                                       
CONECT   22   13   33   47                                                  
CONECT   23   13   34                                                       
CONECT   24   14   34   48                                                  
CONECT   25   14   35                                                       
CONECT   26   15   36                                                       
CONECT   27   15   39                                                       
CONECT   28   29   35   49                                                  
CONECT   29   28   38                                                       
CONECT   30    1    2   16                                                  
CONECT   31    3   17   18                                                  
CONECT   32    4   19   20                                                  
CONECT   33    5   21   22                                                  
CONECT   34    6   23   24                                                  
CONECT   35    7   25   28                                                  
CONECT   36    8   26   40                                                  
CONECT   37    9   38   41                                                  
CONECT   38   29   37   42                                                  
CONECT   39   27   40   42                                                  
CONECT   40   36   39   41                                                  
CONECT   41   37   40   43                                                  
CONECT   42   38   39   44                                                  
CONECT   43   41                                                            
CONECT   44   42                                                            
CONECT   45   18                                                            
CONECT   46   20                                                            
CONECT   47   22                                                            
CONECT   48   24                                                            
CONECT   49   28                                                            
MASTER        0    0    0    0    0    0    0    0   49    0  100    0
END

Synonyms

Value	Source
8-MMK-6	ChEBI

Molecular Formula

C₄₂H₅₈O₂

Average Mass

594.924

Monoisotopic Mass

594.443681108

IUPAC Name

2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3,5-dimethyl-1,4-dihydronaphthalene-1,4-dione

Traditional Name

2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3,5-dimethylnaphthalene-1,4-dione

CAS Registry Number

Not Available

SMILES

[H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=C(C)C=CC=C2C1=O)=C(\C)CCC=C(C)C

InChI Identifier

InChI=1S/C42H58O2/c1-30(2)16-10-17-31(3)18-11-19-32(4)20-12-21-33(5)22-13-23-34(6)24-14-25-35(7)28-29-38-37(9)41(43)40-36(8)26-15-27-39(40)42(38)44/h15-16,18,20,22,24,26-28H,10-14,17,19,21,23,25,29H2,1-9H3/b31-18+,32-20+,33-22+,34-24+,35-28+

InChI Key

HAMLBJAJFRKXHQ-RCIYGOBDSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as sesterterpenoids. These are terpenes composed of five consecutive isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Sesterterpenoids

Direct Parent

Sesterterpenoids

Alternative Parents

Substituents

Sesterterpenoid
Menaquinone
Naphthoquinone
Naphthalene
Aryl ketone
Quinone
Benzenoid
Ketone
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aromatic homopolycyclic compound

Molecular Framework

Aromatic homopolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
logP	12.31	ChemAxon
pKa (Strongest Basic)	-7.2	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	34.14 Å²	ChemAxon
Rotatable Bond Count	17	ChemAxon
Refractivity	198.15 m³·mol⁻¹	ChemAxon
Polarizability	75.86 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	Not Available	2022-08-09	View Spectrum
MS	Mass Spectrum (Electron Ionization)	Not Available	2022-08-06	View Spectrum

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria/Eubacteria	Proteobacteria	1	Cattle

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

64808472

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

101244058

PDB ID

Not Available

ChEBI ID

134356

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for 8-methylmenaquinone-6 (MMDBc0055657)

MOL for #<Metabolite:0x00007fade8601218>

3D MOL for #<Metabolite:0x00007fade8601218>

3D SDF for #<Metabolite:0x00007fade8601218>

3D-SDF for #<Metabolite:0x00007fade8601218>

PDB for #<Metabolite:0x00007fade8601218>

3D PDB for #<Metabolite:0x00007fade8601218>

SMILES for #<Metabolite:0x00007fade8601218>

INCHI for #<Metabolite:0x00007fade8601218>

Structure for #<Metabolite:0x00007fade8601218>

3D Structure for #<Metabolite:0x00007fade8601218>