MiMeDB: Showing metabocard for N(6)-[(indole-3-yl)acetyl]-L-lysine (MMDBc0056199)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2022-06-17 20:19:20 UTC

Update Date

2025-10-07 16:09:39 UTC

Metabolite ID

MMDBc0056199

Metabolite Identification

Common Name

N(6)-[(indole-3-yl)acetyl]-L-lysine

Description

N(6)-[(indole-3-yl)acetyl]-L-lysine is a derivative of the amino acid L-lysine and belongs to the class of acetylated amino acids. There is limited literature available on this metabolite, indicating that further research may be needed to fully understand its biological significance and potential applications.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652306172222192D          

 23 24  0  0  1  0            999 V2000
   -5.7455    6.1714    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5525    6.3429    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6696    3.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3840    3.5407    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4906    5.3868    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9551    3.5407    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.1045    5.7298    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0985    3.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2419    3.5407    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7101    3.6176    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9564    3.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0426    4.7737    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2406    3.9532    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.8496    4.9452    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5275    3.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4738    3.5407    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2406    4.7782    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8130    3.5407    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2621    4.2307    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5275    4.7782    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1883    3.9532    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4738    2.7157    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2406    3.1282    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  2  0  0  0  0
  4  3  1  0  0  0  0
  5  1  1  0  0  0  0
  6  3  1  0  0  0  0
  7  2  1  0  0  0  0
  8  4  1  0  0  0  0
 11  9  1  0  0  0  0
 11 10  2  0  0  0  0
 12  5  2  0  0  0  0
 12 11  1  0  0  0  0
 13  6  1  0  0  0  0
 14  7  2  0  0  0  0
 14 12  1  0  0  0  0
 15  9  1  0  0  0  0
 16 13  1  0  0  0  0
 13 17  1  1  0  0  0
 18  8  1  4  0  0  0
 18 15  2  0  0  0  0
 19 10  1  0  0  0  0
 19 14  1  0  0  0  0
 20 15  1  0  0  0  0
 21 16  2  0  0  0  0
 22 16  1  0  0  0  0
 13 23  1  1  0  0  0
M  END
> <DATABASE_ID>
MMDBc0056199

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@](N)(CCCCN=C(O)CC1=CNC2=CC=CC=C12)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C16H21N3O3/c17-13(16(21)22)6-3-4-8-18-15(20)9-11-10-19-14-7-2-1-5-12(11)14/h1-2,5,7,10,13,19H,3-4,6,8-9,17H2,(H,18,20)(H,21,22)/t13-/m0/s1

> <INCHI_KEY>
FKIGOUKDKBOZID-ZDUSSCGKSA-N

> <FORMULA>
C16H21N3O3

> <MOLECULAR_WEIGHT>
303.362

> <EXACT_MASS>
303.158291548

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
43

> <JCHEM_AVERAGE_POLARIZABILITY>
32.72381565321608

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-2-amino-6-{[1-hydroxy-2-(1H-indol-3-yl)ethylidene]amino}hexanoic acid

> <JCHEM_LOGP>
-1.37455438868291

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
4.210894035388955

> <JCHEM_PKA_STRONGEST_ACIDIC>
2.111773822325156

> <JCHEM_PKA_STRONGEST_BASIC>
9.527049704049404

> <JCHEM_POLAR_SURFACE_AREA>
111.7

> <JCHEM_REFRACTIVITY>
83.5834

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(2S)-2-amino-6-{[1-hydroxy-2-(1H-indol-3-yl)ethylidene]amino}hexanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-JUN-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-JUN-22         0                                  
HETATM    1  C   UNK     0     -10.725  11.520   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0     -12.231  11.840   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -3.117   7.379   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.450   6.609   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0     -10.249  10.055   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.783   6.609   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0     -13.262  10.696   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -5.784   7.379   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -9.785   6.609   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0     -12.525   6.753   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0     -11.119   7.379   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0     -11.280   8.911   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -0.449   7.379   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0     -12.786   9.231   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -8.451   7.379   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       0.885   6.609   0.000  0.00  0.00           C+0
HETATM   17  N   UNK     0      -0.449   8.919   0.000  0.00  0.00           N+0
HETATM   18  N   UNK     0      -7.118   6.609   0.000  0.00  0.00           N+0
HETATM   19  N   UNK     0     -13.556   7.897   0.000  0.00  0.00           N+0
HETATM   20  O   UNK     0      -8.451   8.919   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0       2.218   7.379   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0       0.885   5.069   0.000  0.00  0.00           O+0
HETATM   23  H   UNK     0      -0.449   5.839   0.000  0.00  0.00           H+0
CONECT    1    2    5                                                       
CONECT    2    1    7                                                       
CONECT    3    4    6                                                       
CONECT    4    3    8                                                       
CONECT    5    1   12                                                       
CONECT    6    3   13                                                       
CONECT    7    2   14                                                       
CONECT    8    4   18                                                       
CONECT    9   11   15                                                       
CONECT   10   11   19                                                       
CONECT   11    9   10   12                                                  
CONECT   12    5   11   14                                                  
CONECT   13    6   16   17   23                                             
CONECT   14    7   12   19                                                  
CONECT   15    9   18   20                                                  
CONECT   16   13   21   22                                                  
CONECT   17   13                                                            
CONECT   18    8   15                                                       
CONECT   19   10   14                                                       
CONECT   20   15                                                            
CONECT   21   16                                                            
CONECT   22   16                                                            
CONECT   23   13                                                            
MASTER        0    0    0    0    0    0    0    0   23    0   48    0
END

Synonyms

Value	Source
N6-[(indol-3-yl)Acetyl]-L-lysine	ChEBI
N6-[(Indole-3-yl)acetyl]-L-lysine	ChEBI
Indole-3-acetyl-epsilon-lysine	MeSH
IAA-lysine	MeSH
Indoleacetic acid-lysine	MeSH

Molecular Formula

C₁₆H₂₁N₃O₃

Average Mass

303.362

Monoisotopic Mass

303.158291548

IUPAC Name

(2S)-2-amino-6-{[1-hydroxy-2-(1H-indol-3-yl)ethylidene]amino}hexanoic acid

Traditional Name

(2S)-2-amino-6-{[1-hydroxy-2-(1H-indol-3-yl)ethylidene]amino}hexanoic acid

CAS Registry Number

Not Available

SMILES

[H][C@](N)(CCCCN=C(O)CC1=CNC2=CC=CC=C12)C(O)=O

InChI Identifier

InChI=1S/C16H21N3O3/c17-13(16(21)22)6-3-4-8-18-15(20)9-11-10-19-14-7-2-1-5-12(11)14/h1-2,5,7,10,13,19H,3-4,6,8-9,17H2,(H,18,20)(H,21,22)/t13-/m0/s1

InChI Key

FKIGOUKDKBOZID-ZDUSSCGKSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

L-alpha-amino acids

Alternative Parents

Substituents

3-alkylindole
L-alpha-amino acid
Indole
Indole or derivatives
Medium-chain fatty acid
Amino fatty acid
Heterocyclic fatty acid
Substituted pyrrole
Benzenoid
Fatty acid
Fatty acyl
Heteroaromatic compound
Pyrrole
Carboxamide group
Amino acid
Secondary carboxylic acid amide
Organoheterocyclic compound
Azacycle
Carboxylic acid
Monocarboxylic acid or derivatives
Organonitrogen compound
Primary aliphatic amine
Organic oxide
Organopnictogen compound
Organic oxygen compound
Carbonyl group
Organic nitrogen compound
Organooxygen compound
Primary amine
Hydrocarbon derivative
Amine
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

non-proteinogenic L-alpha-amino acid (CHEBI:17328 )
N(6)-acyl-L-lysine (CHEBI:17328 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
logP	-1.4	ChemAxon
pKa (Strongest Acidic)	2.11	ChemAxon
pKa (Strongest Basic)	9.53	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	111.7 Å²	ChemAxon
Rotatable Bond Count	8	ChemAxon
Refractivity	83.58 m³·mol⁻¹	ChemAxon
Polarizability	32.72 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_4) - 70eV, Positive	Not Available	2022-08-08	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	Not Available	2022-08-09	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	Not Available	2022-08-09	View Spectrum

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (eluted)	2025-10-24	370.6
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (eluted)	2025-10-24	248.9
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-24	285.8
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-24	291.9
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-24	291.7
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (eluted)	2025-10-24	208.6
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	813.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-24	616.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-24	265.0
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	146.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-24	394.6
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	171.1
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	110.7
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	224.7
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	593.9
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	123.7
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	228.9
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-24	818.0
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-24	655.1

Retention Indices

Chromatography Type	Peak Label	SMILES	Stationary Phase	Deposition Date	Retention Index
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_1	C[Si](C)(C)OC(CC1=C[NH]C2=CC=CC=C12)=NCCCC[C@H](N)C(=O)O	standard non polar	2025-10-24	2467.56
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_2	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12	standard non polar	2025-10-24	1986.04
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_3	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O	standard non polar	2025-10-24	1452.62
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_4	C[Si](C)(C)N1C=C(CC(O)=NCCCC[C@H](N)C(=O)O)C2=CC=CC=C21	standard non polar	2025-10-24	2223.48
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_5	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C	standard non polar	2025-10-24	939.548
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_6	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O	standard non polar	2025-10-24	2851.95
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_7	C[Si](C)(C)OC(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)=NCCCC[C@H](N)C(=O)O	standard non polar	2025-10-24	2662.75
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_8	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O[Si](C)(C)C	standard non polar	2025-10-24	2242.92
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_9	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12	standard non polar	2025-10-24	2208.55
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_10	C[Si](C)(C)N([C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O)[Si](C)(C)C	standard non polar	2025-10-24	1131.24
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_11	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O	standard non polar	2025-10-24	1709.4
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_12	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O[Si](C)(C)C	standard non polar	2025-10-24	1768.18
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_13	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C	standard non polar	2025-10-24	1582.62
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_14	C[Si](C)(C)OC(CC1=C[NH]C2=CC=CC=C12)=NCCCC[C@@H](C(=O)O)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	1280.12
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_15	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O	standard non polar	2025-10-24	1593.87
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_16	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	2055.74
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_17	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O[Si](C)(C)C	standard non polar	2025-10-24	1402.56
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_18	C[Si](C)(C)N([C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O)[Si](C)(C)C	standard non polar	2025-10-24	1862.48
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_19	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	2532.83
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_20	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O[Si](C)(C)C	standard non polar	2025-10-24	1782.23
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_21	C[Si](C)(C)OC(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)=NCCCC[C@@H](C(=O)O)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	736.129
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_22	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	2373.86
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_23	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)N([Si](C)(C)C)[Si](C)(C)C	standard non polar	2025-10-24	3198.45
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_1	C[Si](C)(C)OC(CC1=C[NH]C2=CC=CC=C12)=NCCCC[C@H](N)C(=O)O	standard polar	2025-10-24	2467.76
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_2	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12	standard polar	2025-10-24	2111.06
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_3	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O	standard polar	2025-10-24	1846.75
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_4	C[Si](C)(C)N1C=C(CC(O)=NCCCC[C@H](N)C(=O)O)C2=CC=CC=C21	standard polar	2025-10-24	2100.24
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_5	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C	standard polar	2025-10-24	1326.37
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_6	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O	standard polar	2025-10-24	2000.18
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_7	C[Si](C)(C)OC(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)=NCCCC[C@H](N)C(=O)O	standard polar	2025-10-24	2105.38
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_8	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O[Si](C)(C)C	standard polar	2025-10-24	2173.07
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_9	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12	standard polar	2025-10-24	2575.37
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_10	C[Si](C)(C)N([C@@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)C(=O)O)[Si](C)(C)C	standard polar	2025-10-24	1770.32
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_11	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O	standard polar	2025-10-24	2606.75
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_12	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O[Si](C)(C)C	standard polar	2025-10-24	2545.55
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_13	C[Si](C)(C)OC(=O)[C@@H](N)CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C	standard polar	2025-10-24	2011.51
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_14	C[Si](C)(C)OC(CC1=C[NH]C2=CC=CC=C12)=NCCCC[C@@H](C(=O)O)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	2117.12
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_15	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O	standard polar	2025-10-24	2654.15
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_16	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(O)CC1=C[NH]C2=CC=CC=C12)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	2032.27
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_17	C[Si](C)(C)N[C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O[Si](C)(C)C	standard polar	2025-10-24	1552.5
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_18	C[Si](C)(C)N([C@@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)C(=O)O)[Si](C)(C)C	standard polar	2025-10-24	2039.98
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_19	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(CC1=C[NH]C2=CC=CC=C12)O[Si](C)(C)C)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	2410.0
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_20	C[Si](C)(C)N[C@@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)C(=O)O[Si](C)(C)C	standard polar	2025-10-24	1522.72
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_21	C[Si](C)(C)OC(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)=NCCCC[C@@H](C(=O)O)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	2276.55
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_22	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(O)CC1=CN([Si](C)(C)C)C2=CC=CC=C12)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	3572.09
Gas Chromatography	N(6)-[(indole-3-yl)acetyl]-L-lysine_TMS_23	C[Si](C)(C)OC(=O)[C@H](CCCCN=C(CC1=CN([Si](C)(C)C)C2=CC=CC=C12)O[Si](C)(C)C)N([Si](C)(C)C)[Si](C)(C)C	standard polar	2025-10-24	1456.35

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria/Eubacteria	Proteobacteria	1

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

141640

KEGG Compound ID

C04211

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

161240

PDB ID

Not Available

ChEBI ID

17328

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for N(6)-[(indole-3-yl)acetyl]-L-lysine (MMDBc0056199)

MOL for #<Metabolite:0x00007f9acc972f70>

3D MOL for #<Metabolite:0x00007f9acc972f70>

3D SDF for #<Metabolite:0x00007f9acc972f70>

3D-SDF for #<Metabolite:0x00007f9acc972f70>

PDB for #<Metabolite:0x00007f9acc972f70>

3D PDB for #<Metabolite:0x00007f9acc972f70>

SMILES for #<Metabolite:0x00007f9acc972f70>

INCHI for #<Metabolite:0x00007f9acc972f70>

Structure for #<Metabolite:0x00007f9acc972f70>

3D Structure for #<Metabolite:0x00007f9acc972f70>