Showing metabocard for L-Selenocysteine (MMDBc0057152)
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| Version | 2.0 | ||||||||||||||
| Status | Detected and Quantified | ||||||||||||||
| Creation Date | 2022-11-09 19:17:03 UTC | ||||||||||||||
| Update Date | 2025-10-07 16:09:52 UTC | ||||||||||||||
| Metabolite ID | MMDBc0057152 | ||||||||||||||
| Metabolite Identification | |||||||||||||||
| Common Name | L-Selenocysteine | ||||||||||||||
| Description | L-Selenocysteine is a naturally occurring amino acid and a member of the chemical class of selenoamino acids. Its chemical structure features a selenium atom replacing the sulfur atom in cysteine, which allows it to participate in various biochemical pathways. L-Selenocysteine is crucial for the synthesis of selenoproteins, including glutathione peroxidase (GPX), a key antioxidant enzyme that protects cells from oxidative damage (PMID:31082108 ). It is involved in detoxification processes, as it helps restore biothiol levels and counteracts mercury (II) ion toxicity (PMID:39884041 ). Additionally, L-selenocysteine has been shown to influence biofilm formation in certain bacterial strains, demonstrating a regulatory effect at specific concentrations (PMID:38475877 ). It also plays a role in cardiovascular protection through its derivative, Se-methyl L-selenocysteine (PMID:38019326 ). Furthermore, studies indicate that L-selenocysteine can induce apoptosis in HepG-2 cells via reactive oxygen species-mediated signaling pathways, highlighting its potential anticancer properties (PMID:35716289 ). Overall, L-selenocysteine is a vital metabolite with diverse roles in both chemistry and biology. | ||||||||||||||
| Structure |  | ||||||||||||||
| Synonyms |
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| Molecular Formula | C3H6NO2Se | ||||||||||||||
| Average Mass | 167.057 | ||||||||||||||
| Monoisotopic Mass | 167.956375 | ||||||||||||||
| IUPAC Name | Not Available | ||||||||||||||
| Traditional Name | Not Available | ||||||||||||||
| CAS Registry Number | Not Available | ||||||||||||||
| SMILES | Not Available | ||||||||||||||
| InChI Identifier | Not Available | ||||||||||||||
| InChI Key | FDKWRPBBCBCIGA-REOHCLBHSA-N | ||||||||||||||
| Chemical Taxonomy | |||||||||||||||
| Description | Belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. | ||||||||||||||
| Kingdom | Organic compounds | ||||||||||||||
| Super Class | Organic acids and derivatives | ||||||||||||||
| Class | Carboxylic acids and derivatives | ||||||||||||||
| Sub Class | Amino acids, peptides, and analogues | ||||||||||||||
| Direct Parent | L-alpha-amino acids | ||||||||||||||
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| Substituents |
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| Molecular Framework | Aliphatic acyclic compounds | ||||||||||||||
| External Descriptors | Not Available | ||||||||||||||
| Functional Ontology | |||||||||||||||
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| Physical Properties | |||||||||||||||
| State | Not Available | ||||||||||||||
| Predicted Properties | Not Available | ||||||||||||||
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| Cellular Locations | Not Available | ||||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||||
| Tissue Locations | Not Available | ||||||||||||||
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| Pathways | Not Available | ||||||||||||||
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| HMDB ID | Not Available | ||||||||||||||
| DrugBank ID | Not Available | ||||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||||
| FooDB ID | Not Available | ||||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||||
| Chemspider ID | Not Available | ||||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||||
| BioCyc ID | Not Available | ||||||||||||||
| BiGG ID | Not Available | ||||||||||||||
| Wikipedia Link | Not Available | ||||||||||||||
| METLIN ID | Not Available | ||||||||||||||
| PubChem Compound | 6326983 | ||||||||||||||
| PDB ID | Not Available | ||||||||||||||
| ChEBI ID | Not Available | ||||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||||
| CMMC Knowledgebase | Not Available | ||||||||||||||
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