Showing metabocard for Fumonisin B4 (MMDBc0060707)
Microbial
| Record Information | |||||||||||||||||||||
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| Version | 1.0 | ||||||||||||||||||||
| Status | Detected and Quantified | ||||||||||||||||||||
| Creation Date | 2025-10-02 21:58:37 UTC | ||||||||||||||||||||
| Update Date | 2025-10-08 21:35:15 UTC | ||||||||||||||||||||
| Metabolite ID | MMDBc0060707 | ||||||||||||||||||||
| Metabolite Identification | |||||||||||||||||||||
| Common Name | Fumonisin B4 | ||||||||||||||||||||
| Description | Fumonisin B4 is a member of the fumonisin chemical class, which comprises a group of mycotoxins produced by certain fungi, particularly Fusarium species. Its chemical structure features a long-chain fatty acid moiety and a unique tricarballylic acid backbone, which is characteristic of fumonisins. Fumonisin B4 is involved in various biochemical pathways, including its interaction with human serum albumin, as demonstrated in studies examining the toxic impacts of fumonisins on zebrafish embryos (PMID:37238625 ). Additionally, the production of fumonisin B4 can be influenced by metabolic factors such as lactate and starch, indicating its role in fungal secondary metabolism (PMID:20003296 ). Genetic studies have shown that deletion mutants in the fumonisin biosynthetic pathway can lead to the production of homologues of fumonisin B4 that lack certain functional groups, further elucidating its structural characteristics and biosynthetic origins (PMID:17147424 ). This underscores the complexity of its synthesis and the biological processes in which it is involved, highlighting its significance within the broader context of mycotoxin research. | ||||||||||||||||||||
| Structure |  | ||||||||||||||||||||
| Synonyms | Not Available | ||||||||||||||||||||
| Molecular Formula | C34H59NO13 | ||||||||||||||||||||
| Average Mass | 689.84 | ||||||||||||||||||||
| Monoisotopic Mass | 689.398640964 | ||||||||||||||||||||
| IUPAC Name | Not Available | ||||||||||||||||||||
| Traditional Name | Not Available | ||||||||||||||||||||
| CAS Registry Number | Not Available | ||||||||||||||||||||
| SMILES | Not Available | ||||||||||||||||||||
| InChI Identifier | Not Available | ||||||||||||||||||||
| InChI Key | WYYKRDVIBOEORL-JLCKPESSSA-N | ||||||||||||||||||||
| Chemical Taxonomy | |||||||||||||||||||||
| Description | Belongs to the class of organic compounds known as fumonisins. These are diesters of propane-1,2,3-tricarboxylic acid (TCA) and similar long-chain aminopolyol backbones (for FB1: 2S-amino-12S,16R-dimethyl-3S,5R,10R,14S,15R-pentahydroxyeicosane). Structurally, fumonisins resemble the sphingoid bases sphinganine (SA) and sphingosine (SO) to which TCA groups have been added at the C-14 and C-15 positions. | ||||||||||||||||||||
| Kingdom | Organic compounds | ||||||||||||||||||||
| Super Class | Organic acids and derivatives | ||||||||||||||||||||
| Class | Carboxylic acids and derivatives | ||||||||||||||||||||
| Sub Class | Fumonisins | ||||||||||||||||||||
| Direct Parent | Fumonisins | ||||||||||||||||||||
| Alternative Parents | |||||||||||||||||||||
| Substituents |
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| Molecular Framework | Aliphatic acyclic compounds | ||||||||||||||||||||
| External Descriptors |
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| Functional Ontology | |||||||||||||||||||||
| Not Available | |||||||||||||||||||||
| Physical Properties | |||||||||||||||||||||
| State | Not Available | ||||||||||||||||||||
| Predicted Properties | Not Available | ||||||||||||||||||||
| Spectra | |||||||||||||||||||||
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| Biological Properties | |||||||||||||||||||||
| Cellular Locations | Not Available | ||||||||||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||||||||||
| Tissue Locations | Not Available | ||||||||||||||||||||
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| Human Proteins and Enzymes | |||||||||||||||||||||
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| Pathways |
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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| Metabolic Reactions | |||||||||||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| Health Effects and Bioactivity | |||||||||||||||||||||
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| External Links | |||||||||||||||||||||
| HMDB ID | Not Available | ||||||||||||||||||||
| DrugBank ID | Not Available | ||||||||||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||||||||||
| FooDB ID | Not Available | ||||||||||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||||||||||
| Chemspider ID | Not Available | ||||||||||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||||||||||
| BioCyc ID | Not Available | ||||||||||||||||||||
| BiGG ID | Not Available | ||||||||||||||||||||
| Wikipedia Link | Fumonisin B4 | ||||||||||||||||||||
| METLIN ID | Not Available | ||||||||||||||||||||
| PubChem Compound | 42608359 | ||||||||||||||||||||
| PDB ID | Not Available | ||||||||||||||||||||
| ChEBI ID | Not Available | ||||||||||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||||||||||
| CMMC Knowledgebase | WYYKRDVIBOEORL-JLCKPESSSA-N | ||||||||||||||||||||
| References | |||||||||||||||||||||
| Synthesis Reference | Not Available | ||||||||||||||||||||
| General References |
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