Showing metabocard for COPROPORPHYRIN III (MMDBc0060708)
Microbial
Human
Co-metabolite
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 21:59:28 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:15 UTC | ||||||||||||
| Metabolite ID | MMDBc0060708 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | COPROPORPHYRIN III | ||||||||||||
| Description | COPROPORPHYRIN III is a member of the porphyrin chemical class, specifically a type of tetrapyrrole. Its chemical structure consists of four pyrrole rings interconnected by methine bridges, with two propionic acid side chains that can be decarboxylated to form other porphyrins. In biological contexts, COPROPORPHYRIN III is involved in various metabolic pathways, particularly in heme biosynthesis, where it serves as a precursor to protoporphyrin IX through the action of coproheme decarboxylases, which convert it by oxidatively decarboxylating two propionate groups to form vinyl groups (PMID:40803046 ). Additionally, it has been identified as a metabolite of skin microbiota and has applications in photodynamic therapy, where it acts as a photosensitizer to generate reactive oxygen species (ROS) for bacterial inactivation (PMID:40921233 ). The uptake of COPROPORPHYRIN III is facilitated by OATP1B1/1B3 transporters in hepatocytes, highlighting its relevance in metabolic processes (PMID:40540978 ). Furthermore, it has been detected in various microbial co-cultures, indicating its role in microbial interactions (PMID:40864852 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C36H38N4O8 | ||||||||||||
| Average Mass | 654.72 | ||||||||||||
| Monoisotopic Mass | 654.2689642 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | XNBNKCLBGTWWSD-UJJXFSCMSA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Human Proteins and Enzymes | |||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| External Links | Not Available | ||||||||||||
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| Synthesis Reference | Not Available | ||||||||||||
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