Showing metabocard for Amphibactin H (MMDBc0060730)
Microbial
| Record Information | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:22:18 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:17 UTC | ||||||||||||
| Metabolite ID | MMDBc0060730 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Amphibactin H | ||||||||||||
| Description | Amphibactin H is a siderophore belonging to the chemical class of catecholates. Its chemical structure features a hydroxamate functional group that facilitates iron chelation, which is crucial for its role in microbial iron acquisition. Amphibactin H is synthesized through a biosynthetic pathway involving non-ribosomal peptide synthetases, which assemble the molecule from amino acid precursors. In addition to its iron-binding properties, studies have demonstrated the interaction of various transition metal ions (M3+) with amphibactin, revealing that cobalt (Co) and gallium (Ga) form stable complexes with this siderophore, indicating its potential versatility in metal ion coordination (PMID:33273481 ). This interaction underlines amphibactin H's importance not only in iron transport but also in the modulation of metal ion availability in microbial environments. The ability of amphibactin H to bind different metal ions may influence the biological pathways it participates in, including those related to nutrient uptake and microbial competition. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C40H73N7O13 | ||||||||||||
| Average Mass | 860.06 | ||||||||||||
| Monoisotopic Mass | 859.526635439 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | UNCBCVBICFWAOW-UHFFFAOYNA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Functional Ontology | |||||||||||||
| Not Available | |||||||||||||
| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
| Spectra | |||||||||||||
| Not Available | |||||||||||||
| Chromatographic Retention Times and Retention Indices | |||||||||||||
| Retention Times | Not Available | ||||||||||||
| Retention Indices | Not Available | ||||||||||||
| Biological Properties | |||||||||||||
| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
| Associated OMIM IDs | |||||||||||||
| Human Proteins and Enzymes | |||||||||||||
| |||||||||||||
| Human Pathways | |||||||||||||
| Pathways |
| ||||||||||||
| Microbial Pathways | |||||||||||||
| Pathways | Not Available | ||||||||||||
| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
| |||||||||||||
| Health Effects and Bioactivity | |||||||||||||
| |||||||||||||
| Microbial Sources | |||||||||||||
| |||||||||||||
| Exposure Sources | |||||||||||||
| Other Exposures |
| ||||||||||||
| Host Biospecimen and Location | |||||||||||||
| |||||||||||||
| External Links | |||||||||||||
| CMMC Knowledgebase | UNCBCVBICFWAOW-UHFFFAOYSA-N | ||||||||||||
| General References | |||||||||||||
| |||||||||||||
