Showing metabocard for Anabaenopeptin F (MMDBc0060733)
Microbial
| Record Information | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:24:43 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:17 UTC | ||||||||||||
| Metabolite ID | MMDBc0060733 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Anabaenopeptin F | ||||||||||||
| Description | Anabaenopeptin F is a cyclic peptide belonging to the class of non-proteinogenic amino acid-containing metabolites. Its chemical structure features a unique arrangement of amino acids, including the non-proteinogenic homotyrosine, which has been synthesized using metallaphotoredox catalysis to address synthetic challenges (PMID:37921761 ). The total synthesis of anabaenopeptin F has confirmed the stereochemistry of its isoleucine residue (PMID:37921761 ). Biologically, anabaenopeptin F exhibits potent inhibitory activity against carboxypeptidase B in the low nanomolar range, indicating its potential role in protease inhibition (PMID:37921761 ). This metabolite has been isolated alongside various other compounds from cyanobacterial blooms, highlighting its presence in aquatic environments (PMID:22280481 ). Notably, variants of anabaenopeptin F have been characterized, showcasing the diversity of cyclic peptides produced by cyanobacteria (PMID:21488115 ). Furthermore, its toxicity has been confirmed through intraperitoneal tests in mice, where it was identified as a major contaminant in bloom extracts (PMID:24031304 ). Anabaenopeptin F also contributes to the lysis of Microcystis aeruginosa cell lines, suggesting its involvement in complex ecological interactions (PMID:18008101 ). | ||||||||||||
| Structure | |||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C42H62N10O9 | ||||||||||||
| Average Mass | 851.019 | ||||||||||||
| Monoisotopic Mass | 850.470123616 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | RAUPUVQHUFXDQT-QXYAEKBZSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Functional Ontology | |||||||||||||
| Not Available | |||||||||||||
| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
| Spectra | |||||||||||||
| Not Available | |||||||||||||
| Chromatographic Retention Times and Retention Indices | |||||||||||||
| Retention Times | Not Available | ||||||||||||
| Retention Indices | Not Available | ||||||||||||
| Biological Properties | |||||||||||||
| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
| Associated OMIM IDs | |||||||||||||
| Human Proteins and Enzymes | |||||||||||||
| |||||||||||||
| Human Pathways | |||||||||||||
| Pathways |
| ||||||||||||
| Microbial Pathways | |||||||||||||
| Pathways | Not Available | ||||||||||||
| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
| |||||||||||||
| Health Effects and Bioactivity | |||||||||||||
| |||||||||||||
| Microbial Sources | |||||||||||||
| |||||||||||||
| Exposure Sources | |||||||||||||
| Other Exposures |
| ||||||||||||
| Host Biospecimen and Location | |||||||||||||
| |||||||||||||
| External Links | |||||||||||||
| External Links | Not Available | ||||||||||||
| General References | |||||||||||||
| |||||||||||||