Showing metabocard for Bamicetin (MMDBc0060740)
Microbial
| Record Information | |||||||||||||
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:30:21 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:17 UTC | ||||||||||||
| Metabolite ID | MMDBc0060740 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Bamicetin | ||||||||||||
| Description | Bamicetin is a nucleoside antibiotic belonging to the chemical class of 4-aminohexosyl cytosine derivatives. Its chemical structure features a hexose sugar linked to a cytosine base, which contributes to its biological activity. Bamicetin has been isolated from marine actinomycetes and exhibits antimicrobial properties, particularly against Mycobacterium avium complex (MAC). In vitro and in vivo studies have demonstrated its anti-MAC activities, highlighting its potential as a therapeutic agent (PMID:40850776 ). Additionally, bamicetin has been identified alongside other nucleoside antibiotics, showcasing its presence in diverse Streptomyces species (PMID:25522318 ). The minimum inhibitory concentration (MIC) of bamicetin has been reported at 16 µg/mL, indicating its effectiveness in inhibiting bacterial growth (PMID:25522318 ). Structurally, bamicetin shares similarities with other antibiotics in its class, such as amicetin and blasticidin S, although it is distinct in lacking an aminoacyl moiety, which may influence its pharmacological properties (PMID:371683 ). This structural uniqueness, combined with its demonstrated antibacterial activity, positions bamicetin as a compound of interest for further research in antimicrobial therapy. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C28H40N6O9 | ||||||||||||
| Average Mass | 604.661 | ||||||||||||
| Monoisotopic Mass | 604.285676892 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | RYBQPRIRVSUQBG-UHFFFAOYNA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| CMMC Knowledgebase | RYBQPRIRVSUQBG-UHFFFAOYSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
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