Showing metabocard for Baumycins (MMDBc0060742)
Microbial
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:32:00 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:17 UTC | ||||||||||||
| Metabolite ID | MMDBc0060742 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Baumycins | ||||||||||||
| Description | Baumycins is a glycosylated anthracycline, a chemical class known for its significance in cancer therapy. Chemically, baumycins are characterized by an unusual acetal moiety attached to the daunosamine component, which is hydrolyzed during the acidic extraction process of daunorubicin from fermentation broth (PMID:23885759 ). These metabolites are coproduced alongside the clinically important anticancer agents daunorubicin and doxorubicin, both derived from the bacterium Streptomyces peucetius (PMID:23885759 ). Baumycins may play a role in the metabolism of daunorubicin (DNR) and doxorubicin (DXR) to acid-sensitive compounds, a pathway that is potentially linked to the presence of baumycins in various DNR-producing bacteria (PMID:9573189 ). Additionally, the DnrH protein, which exhibits similarities to known glycosyl transferases, is thought to facilitate the conversion of DNR into its polyglycosylated forms, further implicating baumycins in the biosynthetic pathways of these important therapeutic agents (PMID:8955419 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C34H43NO13 | ||||||||||||
| Average Mass | 673.712 | ||||||||||||
| Monoisotopic Mass | 673.273440449 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | MWURQTZZKGQQIE-UHFFFAOYNA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| CMMC Knowledgebase | MWURQTZZKGQQIE-UHFFFAOYSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
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