Showing metabocard for Cembrene (MMDBc0060745)
Microbial
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| Version | 2.0 | |||||||||||||||
| Status | Detected and Quantified | |||||||||||||||
| Creation Date | 2025-10-02 22:34:23 UTC | |||||||||||||||
| Update Date | 2025-10-08 21:35:18 UTC | |||||||||||||||
| Metabolite ID | MMDBc0060745 | |||||||||||||||
| Metabolite Identification | ||||||||||||||||
| Common Name | Cembrene | |||||||||||||||
| Description | Cembrene is a diterpene, a class of chemical compounds characterized by a molecular structure that consists of four isoprene units. This compound is involved in various biosynthetic pathways, notably in the production of cembrene-type diterpenes from geranylgeranyl diphosphate (GGPP) through the action of specific enzymes like SpTS1, which exhibits substrate promiscuity (PMID:41027039 ). Cembrene A, a notable variant, has been identified in essential oils, where it coexists with other terpenes like (Z,E)-α-farnesene (PMID:40638914 ). Molecular docking studies indicate that cembrene A interacts with key bacterial proteins, including dihydrofolate reductase (DHFR) and DNA gyrase, suggesting potential roles in microbial pathways (PMID:40638914 ). Furthermore, the biosynthesis of cembrene B γ-lactone has been successfully reconstituted in heterologous hosts, highlighting its structural significance within the briarane diterpenoid family (PMID:40514549 ). Additionally, cembrene levels are influenced by genetic modifications in plants, as seen in transgenic tobacco, where key floral terpenes, including cembrene, are significantly increased (PMID:39256664 ). Overall, cembrene and its derivatives represent a complex interplay of chemistry and biology, with implications for both natural product synthesis and potential therapeutic applications. | |||||||||||||||
| Structure |  | |||||||||||||||
| Synonyms | Not Available | |||||||||||||||
| Molecular Formula | C20H32 | |||||||||||||||
| Average Mass | 272.476 | |||||||||||||||
| Monoisotopic Mass | 272.25040103 | |||||||||||||||
| IUPAC Name | Not Available | |||||||||||||||
| Traditional Name | Not Available | |||||||||||||||
| CAS Registry Number | Not Available | |||||||||||||||
| SMILES | Not Available | |||||||||||||||
| InChI Identifier | Not Available | |||||||||||||||
| InChI Key | DMHADBQKVWXPPM-HPKGDXISNA-N | |||||||||||||||
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| Physical Properties | ||||||||||||||||
| State | Not Available | |||||||||||||||
| Predicted Properties | Not Available | |||||||||||||||
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| Retention Times | Not Available | |||||||||||||||
| Retention Indices | Not Available | |||||||||||||||
| Biological Properties | ||||||||||||||||
| Cellular Locations | Not Available | |||||||||||||||
| Biospecimen Locations | Not Available | |||||||||||||||
| Tissue Locations | Not Available | |||||||||||||||
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| Pathways | Not Available | |||||||||||||||
| Metabolic Reactions | ||||||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | ||||||||||||||||
| CMMC Knowledgebase | DMHADBQKVWXPPM-HPKGDXISSA-N | |||||||||||||||
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