Showing metabocard for Cinchonine (MMDBc0060749)
Microbial
| Record Information | |||||||||||||
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:37:36 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:18 UTC | ||||||||||||
| Metabolite ID | MMDBc0060749 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Cinchonine | ||||||||||||
| Description | Cinchonine is a natural alkaloid belonging to the class of quinoline derivatives. Its chemical structure features a bicyclic system comprising a quinoline moiety, which is characterized by a fused benzene and pyridine ring. In biological contexts, cinchonine is involved in several metabolic pathways, particularly those related to endoplasmic reticulum (ER) stress modulation. For instance, pharmacological studies have shown that cinchonine acts as an ER stress activator, influencing cellular responses and pathway specificity (PMID:40528684 ). Additionally, it has been identified as a component in various extracts, such as açaí, highlighting its presence in natural products (PMID:40563277 ). The compound also demonstrates potential in electrochemical applications, where it can be deposited onto platinum surfaces for analytical purposes (PMID:40218727 ). Moreover, cinchonine has been utilized as a biocompatible catalyst in carbon dioxide valorization processes, indicating its versatility in both synthetic and environmental chemistry (PMID:40134351 ). Overall, cinchonine exemplifies the intersection of organic chemistry and biological activity, making it a compound of interest in both research and application. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C19H22N2O | ||||||||||||
| Average Mass | 294.398 | ||||||||||||
| Monoisotopic Mass | 294.173213336 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | KMPWYEUPVWOPIM-QAMTZSDWSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Description | Belongs to the class of organic compounds known as cinchona alkaloids. These are alkaloids structurally characterized by the presence of the cinchonan skeleton, which consists of a quinoline linked to an azabicyclo[2.2.2]Octane moiety. | ||||||||||||
| Kingdom | Organic compounds | ||||||||||||
| Super Class | Alkaloids and derivatives | ||||||||||||
| Class | Cinchona alkaloids | ||||||||||||
| Sub Class | Not Available | ||||||||||||
| Direct Parent | Cinchona alkaloids | ||||||||||||
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| Substituents |
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| Molecular Framework | Aromatic heteropolycyclic compounds | ||||||||||||
| External Descriptors |
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| Functional Ontology | |||||||||||||
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| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| HMDB ID | Not Available | ||||||||||||
| DrugBank ID | Not Available | ||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||
| FooDB ID | Not Available | ||||||||||||
| KNApSAcK ID | C00050560 | ||||||||||||
| Chemspider ID | Not Available | ||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||
| BioCyc ID | Not Available | ||||||||||||
| BiGG ID | Not Available | ||||||||||||
| Wikipedia Link | Cinchonine | ||||||||||||
| METLIN ID | Not Available | ||||||||||||
| PubChem Compound | 90454 | ||||||||||||
| PDB ID | Not Available | ||||||||||||
| ChEBI ID | Not Available | ||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||
| CMMC Knowledgebase | KMPWYEUPVWOPIM-QAMTZSDWSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
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