Showing metabocard for Congocidin (MMDBc0060752)
Microbial
| Record Information | |||||||||||||
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:40:02 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:18 UTC | ||||||||||||
| Metabolite ID | MMDBc0060752 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Congocidin | ||||||||||||
| Description | Congocidin is a cyclic peptide antibiotic belonging to the class of ribosomally synthesized and post-translationally modified peptides (RiPPs). Its chemical structure features a unique cyclic arrangement that contributes to its bioactivity, as detailed in early studies which elucidated its molecular configuration (PMID:13383835 ). The structure includes a series of amino acids linked in a cyclic formation, which is crucial for its interaction with biological targets. Congocidin is involved in various biochemical pathways, particularly in its role as an antimicrobial agent. It exerts its effects by disrupting bacterial cell membrane integrity and inhibiting essential cellular processes. This mechanism of action is significant in the context of antibiotic resistance, as it provides insights into alternative therapeutic strategies against resistant bacterial strains. The understanding of congocidin's chemical properties and its interactions with cellular components is vital for the development of new antibiotics and therapeutic agents. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C18H26N10O3 | ||||||||||||
| Average Mass | 430.473 | ||||||||||||
| Monoisotopic Mass | 430.218934737 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | FEILMVGZFWHKPV-UHFFFAOYSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Description | Belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids. | ||||||||||||
| Kingdom | Organic compounds | ||||||||||||
| Super Class | Organic acids and derivatives | ||||||||||||
| Class | Carboxylic acids and derivatives | ||||||||||||
| Sub Class | Amino acids, peptides, and analogues | ||||||||||||
| Direct Parent | Alpha amino acid amides | ||||||||||||
| Alternative Parents |
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| Substituents |
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| Molecular Framework | Aromatic heteromonocyclic compounds | ||||||||||||
| External Descriptors | Not Available | ||||||||||||
| Functional Ontology | |||||||||||||
| Not Available | |||||||||||||
| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
| Spectra | |||||||||||||
| Not Available | |||||||||||||
| Biological Properties | |||||||||||||
| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
| Associated OMIM IDs | |||||||||||||
| Human Proteins and Enzymes | |||||||||||||
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| Human Pathways | |||||||||||||
| Pathways |
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| Microbial Pathways | |||||||||||||
| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| Health Effects and Bioactivity | |||||||||||||
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| Microbial Sources | |||||||||||||
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| Other Exposures |
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| Host Biospecimen and Location | |||||||||||||
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| External Links | |||||||||||||
| HMDB ID | Not Available | ||||||||||||
| DrugBank ID | Not Available | ||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||
| FooDB ID | Not Available | ||||||||||||
| KNApSAcK ID | C00018663 | ||||||||||||
| Chemspider ID | Not Available | ||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||
| BioCyc ID | Not Available | ||||||||||||
| BiGG ID | Not Available | ||||||||||||
| Wikipedia Link | Netropsin | ||||||||||||
| METLIN ID | Not Available | ||||||||||||
| PubChem Compound | 3664275 | ||||||||||||
| PDB ID | Not Available | ||||||||||||
| ChEBI ID | Not Available | ||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||
| CMMC Knowledgebase | FEILMVGZFWHKPV-UHFFFAOYSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
| General References |
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