Showing metabocard for Dehydromutactin (MMDBc0060761)
Microbial
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| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:47:21 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:19 UTC | ||||||||||||
| Metabolite ID | MMDBc0060761 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Dehydromutactin | ||||||||||||
| Description | Dehydromutactin is a polyketide metabolite characterized as a shunt product in the biosynthetic pathways of actinorhodin-related compounds. Its chemical structure is derived from octaketide intermediates, which are synthesized through a series of enzymatic reactions involving polyketide synthases. Dehydromutactin has been identified alongside other metabolites such as mutactin and SEK34 in studies of the secondary metabolites produced by Streptomyces species, particularly Streptomyces vietnamensis (PMID:31925390 ). The compound's formation is linked to the cyclase/aromatase enzymes involved in the biosynthesis of anthraquinones, where the deletion of such enzymes leads to the accumulation of dehydromutactin and related compounds (PMID:17722122 ). Additionally, dehydromutactin has been noted for its potential as a low-molecular-weight inhibitor of the Hu protein R (HuR), suggesting its relevance in biochemical studies (PMID:17632515 ). Structural elucidation through spectroscopic techniques has confirmed its classification within the broader context of octaketide-derived metabolites, highlighting its role in the intricate metabolic pathways of actinobacteria (PMID:16124774 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C16H12O5 | ||||||||||||
| Average Mass | 284.267 | ||||||||||||
| Monoisotopic Mass | 284.068473486 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | BHLYFNZONJFBSR-UHFFFAOYSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Description | Belongs to the class of organic compounds known as naphthols and derivatives. These are naphthalene derivatives carrying one or more hydroxyl (-OH) groups at any ring position. | ||||||||||||
| Kingdom | Organic compounds | ||||||||||||
| Super Class | Benzenoids | ||||||||||||
| Class | Naphthalenes | ||||||||||||
| Sub Class | Naphthols and derivatives | ||||||||||||
| Direct Parent | Naphthols and derivatives | ||||||||||||
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| Substituents |
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| Molecular Framework | Aromatic heteropolycyclic compounds | ||||||||||||
| External Descriptors | Not Available | ||||||||||||
| Functional Ontology | |||||||||||||
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| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways |
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| Microbial Pathways | |||||||||||||
| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| HMDB ID | Not Available | ||||||||||||
| DrugBank ID | Not Available | ||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||
| FooDB ID | Not Available | ||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||
| Chemspider ID | Not Available | ||||||||||||
| KEGG Compound ID | Not Available | ||||||||||||
| BioCyc ID | Not Available | ||||||||||||
| BiGG ID | Not Available | ||||||||||||
| Wikipedia Link | Not Available | ||||||||||||
| METLIN ID | Not Available | ||||||||||||
| PubChem Compound | 54685140 | ||||||||||||
| PDB ID | Not Available | ||||||||||||
| ChEBI ID | Not Available | ||||||||||||
| Food Biomarker Ontology | Not Available | ||||||||||||
| CMMC Knowledgebase | BHLYFNZONJFBSR-UHFFFAOYSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
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