Showing metabocard for isochromophilone VI (MMDBc0060772)
Microbial
| Record Information | |||||||||||||
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| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:56:21 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:20 UTC | ||||||||||||
| Metabolite ID | MMDBc0060772 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | isochromophilone VI | ||||||||||||
| Description | Isochromophilone VI is a chlorinated azaphilone alkaloid, a chemical class known for its complex aromatic structures and biological activities. This metabolite has been identified as part of the fermentation products from the fungus ACD-5, particularly when cultivated in brown rice medium, where it was isolated alongside other compounds such as sclerotioramine and isochromophilone IX, based on bioactivity and mass spectrometry analysis (PMID:37206330 ). The biosynthesis of isochromophilone VI is closely linked to specific polyketide synthase (PKS) genes; notably, the knockout of the sclA and sclI genes leads to a loss of pigmentation in mycelia and halts the production of various sclerotiorin-like metabolites, including isochromophilone VI itself (PMID:36708387 ). This indicates its role in the metabolic pathways of fungi, particularly in the biosynthesis of secondary metabolites that may have ecological or pharmacological significance. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C23H28ClNO5 | ||||||||||||
| Average Mass | 433.93 | ||||||||||||
| Monoisotopic Mass | 433.1656007 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | ZQLIAKJHIRHCFA-XHBXSBNINA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Retention Times | Not Available | ||||||||||||
| Retention Indices | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | Not Available | ||||||||||||
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| External Links | Not Available | ||||||||||||
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