Showing metabocard for Leu7-Surfactin (MMDBc0060774)
Microbial
| Record Information | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 22:57:58 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:20 UTC | ||||||||||||
| Metabolite ID | MMDBc0060774 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Leu7-Surfactin | ||||||||||||
| Description | Leu7-Surfactin is a lipopeptide, a class of surfactants characterized by their amphiphilic properties, which enable them to reduce surface tension. Chemically, Leu7-Surfactin consists of a cyclic structure formed by a peptide chain and a fatty acid tail, contributing to its surfactant activity. The peptide backbone is composed of seven amino acids, with leucine being prominent in its sequence, which influences its biological interactions and stability. The synthesis of Leu7-Surfactin involves the non-ribosomal peptide synthetase pathway, a complex enzymatic process that assembles the peptide in a modular fashion, allowing for structural diversity. This metabolite has been isolated and characterized from the endophytic bacterium Bacillus mojavensis RRC 101, which serves as a biocontrol agent against the plant pathogen Fusarium verticillioides (PMID:19371139 ). Leu7-Surfactin's surfactant properties enable it to disrupt microbial membranes, making it effective in biocontrol applications, and it may also play a role in soil health and plant-microbe interactions, although the specifics of these pathways require further investigation. | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C53H93N7O13 | ||||||||||||
| Average Mass | 1036.363 | ||||||||||||
| Monoisotopic Mass | 1035.683136083 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | NJGWOFRZMQRKHT-YPLKSVCJSA-N | ||||||||||||
| Chemical Taxonomy | |||||||||||||
| Functional Ontology | |||||||||||||
| Not Available | |||||||||||||
| Physical Properties | |||||||||||||
| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
| Spectra | |||||||||||||
| Not Available | |||||||||||||
| Biological Properties | |||||||||||||
| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
| Associated OMIM IDs | |||||||||||||
| Human Proteins and Enzymes | |||||||||||||
| |||||||||||||
| Human Pathways | |||||||||||||
| Pathways |
| ||||||||||||
| Microbial Pathways | |||||||||||||
| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
| ||||||||||||
| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
| |||||||||||||
| Health Effects and Bioactivity | |||||||||||||
| |||||||||||||
| Microbial Sources | |||||||||||||
| |||||||||||||
| Exposure Sources | |||||||||||||
| Other Exposures |
| ||||||||||||
| Host Biospecimen and Location | |||||||||||||
| |||||||||||||
| External Links | |||||||||||||
| CMMC Knowledgebase | NJGWOFRZMQRKHT-WGVNQGGSSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
| General References |
| ||||||||||||
