Microbial
Record Information
Version2.0
StatusDetected and Quantified
Creation Date2025-10-02 23:10:08 UTC
Update Date2025-10-08 21:35:21 UTC
Metabolite IDMMDBc0060789
Metabolite Identification
Common NameNobilamide J
DescriptionNobilamide J is a member of the nobilamide chemical class, characterized by its unique structure that includes an amide functional group. This compound has been identified as a metabolite with notable antibiotic properties, specifically exhibiting potent activity against various pathogens. The chemical structure of nobilamide J allows it to interact effectively with bacterial cell membranes, contributing to its antimicrobial effects. In particular, agar diffusion assays have demonstrated that nobilamide J, alongside its N-acyl homologs, A-3302-A and A-3302-B, shows significant antibacterial activity against Lysinibacillus sphaericus, a pathogen associated with severe sepsis and bacteremia in humans (PMID:39456177 ). The pathways involved in its action likely include disruption of bacterial cell wall synthesis and interference with essential cellular processes, underscoring its potential as a therapeutic agent in combating infections caused by resistant strains.
Structure
SynonymsNot Available
Molecular FormulaC44H61N7O9
Average Mass832.012
Monoisotopic Mass831.453076572
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry NumberNot Available
SMILESNot Available
InChI Identifier
Not Available
InChI KeyQPLVWFLTOFPKKP-KDZIRAKRSA-N