Showing metabocard for Pseudobactin (MMDBc0060804)
Microbial
| Record Information | |||||||||||||
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| Version | 2.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 23:22:07 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:22 UTC | ||||||||||||
| Metabolite ID | MMDBc0060804 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Pseudobactin | ||||||||||||
| Description | Pseudobactin is a siderophore belonging to the chemical class of catecholate-type iron chelators. Its chemical structure features a catechol moiety that facilitates iron binding, allowing it to effectively sequester ferric ions from the environment, which is crucial for bacterial survival in iron-limited conditions. Pseudobactin is involved in various biochemical pathways, particularly in the iron uptake mechanisms of Pseudomonas species, such as Pseudomonas capeferrum. The pseudobactin BN7/8 uptake (Pup) system not only imports iron but also regulates its own transcription through a complex signaling pathway involving the N-terminal signaling domain (NTSD) of the outer membrane transporter PupB and the C-terminal CSS domain (CCSSD) of the sigma regulator PupR (PMID:39334875 ). In the absence of ferric pseudobactin, these signaling components form a periplasmic complex that maintains a resting state (PMID:39334875 ). Pseudobactins are also noted for their interaction with iron nanoparticles, which have implications for controlling antibiotic-resistant strains such as Pseudomonas aeruginosa (PMID:31513733 ). Overall, pseudobactin plays a critical role in iron acquisition and regulatory pathways in Pseudomonas species (PMID:24818914 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C42H60N12O16 | ||||||||||||
| Average Mass | 989.01 | ||||||||||||
| Monoisotopic Mass | 988.4250239 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | UGBOUVVZXRMJNM-UHFFFAOYNA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Retention Times | Not Available | ||||||||||||
| Retention Indices | Not Available | ||||||||||||
| Biological Properties | |||||||||||||
| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | Not Available | ||||||||||||
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Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| CMMC Knowledgebase | UGBOUVVZXRMJNM-UHFFFAOYSA-N | ||||||||||||
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