Showing metabocard for Sclerotiorin (MMDBc0060811)
Microbial
| Record Information | |||||||||||||
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| Version | 1.0 | ||||||||||||
| Status | Detected and Quantified | ||||||||||||
| Creation Date | 2025-10-02 23:27:44 UTC | ||||||||||||
| Update Date | 2025-10-08 21:35:23 UTC | ||||||||||||
| Metabolite ID | MMDBc0060811 | ||||||||||||
| Metabolite Identification | |||||||||||||
| Common Name | Sclerotiorin | ||||||||||||
| Description | Sclerotiorin is a member of the azaphilone chemical class, characterized by a unique pyranoquinone core structure. This metabolite has been isolated from various fungal species, including the marine-derived fungus Microsphaeropsis arundinis, where it was identified alongside other sclerotiorin-type azaphilones featuring rare γ-lactone or tetrahydrofuran fragments at the C-3 position (PMID:40168493 ). The biosynthetic pathways of these compounds have been elucidated, revealing the role of the LutB transcription factor in overexpressing pathway-specific genes to produce new sclerotiorin-type azaphilones (PMID:38962874 ). Additionally, a LutC-LutD binary oxidoreductase system has been discovered, contributing to the understanding of the basic biosynthetic pathway of sclerotiorin-type azaphilones (PMID:38962874 ). Sclerotiorin also exhibits antioxidant properties, with its activity measured against that of sclerotioramine, which demonstrated significantly higher antioxidant capacity (PMID:38514498 ). The compound has been identified in various fungal species, including Penicillium sclerotiorum and Clonostachys rosea, highlighting its widespread occurrence in nature (PMID:38051942 ). | ||||||||||||
| Structure |  | ||||||||||||
| Synonyms | Not Available | ||||||||||||
| Molecular Formula | C22H26O5 | ||||||||||||
| Average Mass | 370.445 | ||||||||||||
| Monoisotopic Mass | 370.178023937 | ||||||||||||
| IUPAC Name | Not Available | ||||||||||||
| Traditional Name | Not Available | ||||||||||||
| CAS Registry Number | Not Available | ||||||||||||
| SMILES | Not Available | ||||||||||||
| InChI Identifier | Not Available | ||||||||||||
| InChI Key | CZPXLTLKPOJRMB-QWOULBPOSA-N | ||||||||||||
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| State | Not Available | ||||||||||||
| Predicted Properties | Not Available | ||||||||||||
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| Cellular Locations | Not Available | ||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||
| Tissue Locations | Not Available | ||||||||||||
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| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
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| Metabolic Reactions | |||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
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| External Links | |||||||||||||
| CMMC Knowledgebase | CZPXLTLKPOJRMB-QWOULBPOSA-N | ||||||||||||
| References | |||||||||||||
| Synthesis Reference | Not Available | ||||||||||||
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