Showing metabocard for Tetradecanoylhomoserine (MMDBc0061041)
Microbial
Human
| Record Information | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 2.0 | ||||||||||||||||||||
| Status | Detected and Quantified | ||||||||||||||||||||
| Creation Date | 2025-10-03 02:40:11 UTC | ||||||||||||||||||||
| Update Date | 2025-10-08 21:35:41 UTC | ||||||||||||||||||||
| Metabolite ID | MMDBc0061041 | ||||||||||||||||||||
| Metabolite Identification | |||||||||||||||||||||
| Common Name | Tetradecanoylhomoserine | ||||||||||||||||||||
| Description | Tetradecanoylhomoserine is a member of the acylhomoserine lactone (AHL) chemical class, which are signaling molecules involved in quorum sensing in various bacteria. Its chemical structure features a homoserine lactone core linked to a tetradecanoyl acyl chain, which plays a crucial role in its biological activity. Tetradecanoylhomoserine is synthesized through specific enzymatic pathways that involve the acylation of homoserine, contributing to the regulation of gene expression in response to cell density. This metabolite has been identified in culture supernatants, where it functions as a signaling molecule, influencing bacterial communication and behavior. For instance, chromatography and further chemical analysis have revealed the presence of N-tetradecanoylhomoserine lactone alongside other AHLs, such as 6-carboxy-HHL, indicating its role in complex microbial interactions (PMID:22666003 ). The structural characteristics of tetradecanoylhomoserine facilitate its involvement in these signaling pathways, making it an important compound in the study of bacterial communication mechanisms. | ||||||||||||||||||||
| Structure |  | ||||||||||||||||||||
| Synonyms | Not Available | ||||||||||||||||||||
| Molecular Formula | C18H35NO4 | ||||||||||||||||||||
| Average Mass | 329.481 | ||||||||||||||||||||
| Monoisotopic Mass | 329.256608611 | ||||||||||||||||||||
| IUPAC Name | Not Available | ||||||||||||||||||||
| Traditional Name | Not Available | ||||||||||||||||||||
| CAS Registry Number | Not Available | ||||||||||||||||||||
| SMILES | Not Available | ||||||||||||||||||||
| InChI Identifier | Not Available | ||||||||||||||||||||
| InChI Key | NXPWNQYFYMELCY-UHFFFAOYNA-N | ||||||||||||||||||||
| Chemical Taxonomy | |||||||||||||||||||||
| Functional Ontology | |||||||||||||||||||||
| Not Available | |||||||||||||||||||||
| Physical Properties | |||||||||||||||||||||
| State | Not Available | ||||||||||||||||||||
| Predicted Properties | Not Available | ||||||||||||||||||||
| Spectra | |||||||||||||||||||||
| Not Available | |||||||||||||||||||||
| Biological Properties | |||||||||||||||||||||
| Cellular Locations | Not Available | ||||||||||||||||||||
| Biospecimen Locations | Not Available | ||||||||||||||||||||
| Tissue Locations | Not Available | ||||||||||||||||||||
| Associated OMIM IDs | |||||||||||||||||||||
| Human Proteins and Enzymes | |||||||||||||||||||||
| |||||||||||||||||||||
| Human Pathways | |||||||||||||||||||||
| Pathways |
| ||||||||||||||||||||
| Microbial Pathways | |||||||||||||||||||||
| Pathways | This table shows at most 5 pathways. For the full list of associated pathways: See All Associated Bacterial Pathways
| ||||||||||||||||||||
| Metabolic Reactions | |||||||||||||||||||||
Reactions This table shows at most 20 reactions. For the full list of associated reactions: See All Associated Reactions
| |||||||||||||||||||||
| Health Effects and Bioactivity | |||||||||||||||||||||
| |||||||||||||||||||||
| Microbial Sources | |||||||||||||||||||||
| |||||||||||||||||||||
| Exposure Sources | |||||||||||||||||||||
| Other Exposures |
| ||||||||||||||||||||
| Host Biospecimen and Location | |||||||||||||||||||||
| |||||||||||||||||||||
| External Links | |||||||||||||||||||||
| CMMC Knowledgebase | NXPWNQYFYMELCY-UHFFFAOYSA-N | ||||||||||||||||||||
| References | |||||||||||||||||||||
| Synthesis Reference | Not Available | ||||||||||||||||||||
| General References |
| ||||||||||||||||||||
