Microbe Identification
Microbe nameNeisseria sicca
NCBI Taxonomy ID490
DescriptionNeisseria sicca is a Gram-negative, non-motile, and non-spore-forming microbe that thrives in a temperature range of mesophilic to thermophilic, with a preference for temperatures between 25-37°C. As a chemo-heterotroph, it obtains energy by breaking down complex organic compounds and uses a respiratory type of metabolism, generating energy through the process of oxidative phosphorylation. In terms of its Gram stain, N. sicca is classified as Gram-negative, meaning its cell wall lacks the thick peptidoglycan layer found in Gram-positive bacteria. Instead, it has a thin layer of peptidoglycan and an outer membrane containing lipopolysaccharides. Morphologically, N. sicca is characterized by its coccoid or diplococcal shape, typically forming pairs or chains. Neisseria sicca is found in all body sites, including the respiratory, gastrointestinal, and genitourinary tracts, as well as the skin and mucous membranes. It is an obligate aerobe, requiring oxygen to survive and thrive. In terms of its energy production, N. sicca generates its energy through the breakdown of organic compounds, using oxygen as the final electron acceptor in the process. This is achieved through the action of enzymes such as NADH dehydrogenase and cytochrome c oxidase. One notable aspect of Neisseria sicca is its ability to colonize and infect various host sites, often in association with other microorganisms. For instance, it can be found in the oral cavity, particularly in the crevices and fissures of the teeth and periodontal pockets. Despite its relatively innocuous nature, N. sicca has been implicated in several human diseases, including endocarditis, meningitis, and pneumonia. Its ability to adapt to different environments and hosts highlights its remarkable resilience and adaptability as a microbe.
Microbe Taxonomy
SuperkingdomBacteria
KingdomEubacteria
PhylumProteobacteria
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
Species sicca
Microbe Properties
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceNo
Number of membranesNot Available
Oxygen preferenceNot Available
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Cell arrangementNot Available
SporulationNonsporulating
MetabolismNot Available
Energy sourceChemoheterotroph
Host and Biospecimens
HostBody siteBiospecimenData SourceReference
HumanHuman Oral Microbiome Database (HOMD)20624719
HumanMucosaHuman Microbiome Project28953883
HumanSupragingival plaqueHuman Microbiome Project28953883
HumanLower respiratory tractBacDive34718743
HumanNasopharynxBacDive34718743
HumanPharynxBacDive34718743
HumanBronchiBacDive34718743
HumanGingivaSubgingival plaqueDisbiome25283067