Microbe Identification
Microbe nameClostridium scindens
NCBI Taxonomy ID29347
DescriptionClostridium scindens is a gram-positive, rod-shaped (bacillus) microbe that thrives in a mesophilic environment, with a temperature preference of 25-40°C. This microbe is a heterotroph, obtaining its energy by breaking down organic compounds, specifically in the absence of oxygen. C. scindens is an anaerobe, requiring a low oxygen tolerance, and is therefore found primarily in environments with limited oxygen availability, such as the gut and soil. This microbe produces its energy through anaerobic respiration, breaking down carbohydrates, proteins, and fats to produce ATP. C. scindens is capable of fermenting a wide range of substrates, including sugars, amino acids, and glycerol, producing a variety of end products, including acetate, lactate, and ethanol. As a facultative anaerobe, C. scindens can survive in environments with low oxygen levels, but can also tolerate aerobic conditions. This adaptability allows it to colonize diverse environments, including the human gut, where it can be found in the colon and oral cavities. Additionally, C. scindens is also present in soil and wastewater treatment plants, where it plays a role in decomposing organic matter. Interestingly, C. scindens has been found to have a unique ability to degrade and utilize hydrophobic compounds, such as lipids and waxes, which makes it a valuable asset in bioremediation and biotechnology applications. Furthermore, its ability to tolerate low oxygen levels and produce organic acids as byproducts has led to its investigation as a potential probiotic to promote gut health and improve nutrient extraction.
Microbe Taxonomy
SuperkingdomBacteria
KingdomEubacteria
PhylumFirmicutes
ClassClostridia
OrderClostridiales
FamilyLachnospiraceae
GenusLachnoclostridium
SpeciesClostridium scindens
Microbe Properties
Gram staining propertiesNot Available
ShapeBacilli
MobilityNo
Flagellar presenceNo
Number of membranesNot Available
Oxygen preferenceAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Cell arrangementNot Available
SporulationSporulating
MetabolismFermentative, Bile acid 7-dehydroxylation, Steroid metabolism, Bile salt metabolism, 7α-dehydroxylation, Bile acid metabolism, Bile acid 7α-dehydroxylating
Energy sourceChemoheterotroph
Host and Biospecimens
HostBody siteBiospecimenData SourceReference
HumanLarge intestineBacDive34718743
HumanLarge intestineFecesDisbiome12173102