| Description | Burkholderia ambifaria is a Gram-negative, rod-shaped bacterium that thrives in mesophilic temperatures, classified as a Chemoheterotroph, and can be found in various body sites, including the respiratory, gastrointestinal, and genitourinary tracts, across numerous species, and is known to be a Facultative Anaerobe. The Gram-negative stain characteristic indicates that the bacterium's cell wall contains a thin peptidoglycan layer, making it more resistant to certain antibiotics. Its rod-shaped morphology allows for efficient movement and colonization in various environments. As a mesophilic bacterium, Burkholderia ambifaria prefers moderate temperatures, typically between 20-40°C, which is conducive to its growth and survival in diverse ecosystems. As a Chemoheterotroph, Burkholderia ambifaria relies on organic compounds for energy and carbon sources, obtaining these necessities from its surroundings rather than producing them through photosynthesis or other means. This flexibility in nutrient acquisition enables the bacterium to inhabit a wide range of environments, from soil and water to human and animal hosts. The bacterium's ability to thrive in various body sites is a testament to its adaptability and potential to cause infections in different parts of the body. Being a Facultative Anaerobe, Burkholderia ambifaria can survive in both aerobic and anaerobic conditions, allowing it to colonize diverse niches and evade the host's immune system. Burkholderia ambifaria has been implicated in various infections, including pneumonia, bacteremia, and urinary tract infections, particularly in individuals with compromised immune systems. Its ability to form biofilms and produce virulence factors, such as siderophores and lipopolysaccharides, contributes to its pathogenicity and resistance to antimicrobial agents. The bacterium's genome has been fully sequenced, revealing a complex array of genes involved in virulence, metabolism, and environmental adaptation, which has significant implications for the development of effective treatment strategies and prevention measures. |
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