| Description | Atopobium vaginae DSM 15829 is a Gram-positive, nonsporulating bacterium belonging to the genus Atopobium, which is part of the Actinobacteria phylum. This microbe is predominantly found in the human gastrointestinal tract, particularly within the female vaginal microbiome, where it plays a role in maintaining the delicate balance of microbial communities. A mesophilic organism, A. vaginae thrives optimally at 37°C, which corresponds to normal human body temperature, facilitating its adaptation to host-associated environments. As a chemoheterotroph, A. vaginae derives its energy from organic compounds, although its specific metabolic functions remain largely unknown. The bacterium typically exists in complex biofilms alongside other microbial species in the host gut, contributing to various metabolic processes and influencing local microbial diversity. One notable ecological insight regarding Atopobium vaginae is its association with health and disease states in women. The bacterium has been implicated in various conditions, including bacterial vaginosis, where its abundance can disrupt the typical lactobacillus-dominant microbiome. This shift can lead to increased susceptibility to infections and adverse reproductive outcomes. Understanding A. vaginae's role within the vaginal microbiome not only sheds light on microbial interactions but also underscores the importance of maintaining microbial homeostasis for female reproductive health. |
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