| Description | Uncultured Eggerthella sp. is an anaerobic bacterium predominantly found in the gut microbiota of various hosts, including humans. As a member of the Eggerthellaceae family, it typically resides in the gastrointestinal tract, where it plays a role in the complex microbial ecosystem. Although the specific traits regarding its Gram stain, shape, and cell arrangement remain elusive, studies suggest that Eggerthella species are generally rod-shaped and are known for their association with human health and disease. This microbe is of particular interest due to its potential involvement in various metabolic processes within the gut, including the fermentation of dietary fibers and the production of short-chain fatty acids (SCFAs), which are essential for gut health and systemic metabolism. While the precise energy sources utilized by uncultured Eggerthella sp. have not been fully characterized, similar taxa are known to derive energy from complex carbohydrates and peptides. Furthermore, the presence and abundance of uncultured Eggerthella sp. in the gut microbiome may be influenced by dietary patterns, antibiotic use, and overall gut health. Its role as a member of the gut microbiota underscores the delicate balance within this ecosystem, emphasizing the importance of microbial diversity in maintaining host health. An intriguing ecological insight is that fluctuations in the abundance of Eggerthella species could serve as indicators of gastrointestinal dysbiosis, which is associated with various conditions, including inflammatory bowel disease and metabolic disorders. Thus, uncultured Eggerthella sp. represents not only a key microbial player in gut health but also a potential marker for assessing gut-related diseases. |
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