| Description | Dorea sp. AF36-15AT is a nonsporulating, chemoheterotrophic bacterium primarily found within the intestinal microflora of animals. This microbe exhibits notable capabilities in bile acid metabolism and is involved in the production of deoxycholic acid (DCA) through fermentative processes. These metabolic pathways are particularly significant as they influence the composition and function of the gut microbiome, contributing to the overall health of the host. Dorea sp. AF36-15AT plays a role in the degradation of complex organic materials in the gut, utilizing various substrates derived from dietary fibers and proteins. Its ability to metabolize bile acids suggests a specialization in adapting to the harsh conditions of the intestinal environment, where it can thrive alongside other microbial populations. The production of DCA is particularly interesting, as this bile acid has been implicated in several physiological processes and may affect host lipid metabolism, immune responses, and the modulation of gut flora diversity. Ecologically, Dorea sp. AF36-15AT exemplifies the intricate relationships between host and microbiota, highlighting how specific microbial members can influence metabolic outcomes within the gastrointestinal tract. Furthermore, its presence and metabolic functions could be pivotal in understanding the balance of gut health, potentially impacting conditions such as obesity or gastrointestinal disorders. The study of such microbes not only enriches our knowledge of gut ecology but may also open avenues for therapeutic interventions targeting gut dysbiosis. |
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