| Description | Dorea sp. D27 is a nonsporulating, chemoheterotrophic microbe predominantly found within the gastrointestinal tract of various hosts. This bacterium is noted for its role in secondary bile acid biosynthesis, a critical metabolic process that contributes to the modulation of gut microbiota composition and the enhancement of host health. By converting primary bile acids into secondary bile acids, Dorea sp. D27 plays a significant part in metabolic pathways that impact lipid digestion and absorption, as well as the regulation of cholesterol levels in the host. This microbe's ecological niche in the gut is essential for maintaining a balanced microbiome, where it interacts with numerous other microorganisms to produce metabolites that can affect host metabolism and immune function. The presence of Dorea sp. D27 is often linked with healthier gut environments, as it can help inhibit the growth of pathogenic bacteria through competitive exclusion and the production of antimicrobial compounds. A unique aspect of Dorea sp. D27 is its influence on the production of secondary bile acids, which have been shown to have downstream effects on gut health and systemic metabolism. This highlights its potential role in the prevention of metabolic disorders and the modulation of inflammatory responses in the gut, suggesting that a healthy population of Dorea sp. D27 may contribute positively to the overall well-being of the host organism. Thus, understanding this microbe could lead to novel probiotic therapies aimed at enhancing gut health and preventing disease. |
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