| Description | Faecalibacterium sp. CAG:1138 is a chemoheterotrophic bacterium primarily located in the intestinal microflora of various animals. This microorganism plays a crucial role in the gut ecosystem, contributing to the metabolic processes that facilitate nutrient absorption and the maintenance of gut health. Faecalibacterium spp., including CAG:1138, are known for their ability to ferment dietary fibers, producing short-chain fatty acids (SCFAs) such as butyrate. Butyrate serves as an essential energy source for colonocytes, the cells lining the colon, and has anti-inflammatory properties that contribute to gut homeostasis. The presence of Faecalibacterium sp. CAG:1138 in the gut microbiota is often associated with a healthy intestinal environment. Its abundance tends to decrease in conditions such as inflammatory bowel disease (IBD) and obesity, indicating its potential role as a beneficial bacterium. This strain, along with other members of the Faecalibacterium genus, has garnered attention in microbiome research for its protective effects against gastrointestinal disorders. A unique ecological insight into Faecalibacterium sp. CAG:1138 is its potential impact on the host's immune response. By producing SCFAs and modulating gut barrier function, this microbe may influence the host's susceptibility to various diseases and conditions, underscoring the intricate relationship between gut microbiota and overall health. Promoting the growth of such beneficial microbes could therefore be a promising therapeutic strategy for enhancing gut health and preventing degenerative diseases. |
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