| Description | Subdoligranulum sp. is a Gram-positive, nonsporulating bacterium known for its role in butyrate production within animal intestinal microflora. This microbe is classified as a chemoheterotroph, meaning it derives its energy from organic compounds, which it metabolizes to generate butyrate, a short-chain fatty acid highly beneficial to gut health. Butyrate serves as an energy source for colonocytes, the cells lining the colon, and plays a pivotal role in maintaining a healthy gut environment by supporting epithelial integrity and exerting anti-inflammatory effects. Subdoligranulum sp. is found in the intestines of various animals, including humans, where it contributes to a balanced gut microbiome. The presence of this bacterium can influence the overall composition of the intestinal flora, impacting metabolic health and immune function. Furthermore, the balance between butyrate-producing bacteria and other microbial species is crucial for preventing dysbiosis, which is associated with various gastrointestinal diseases and conditions such as inflammatory bowel disease. Ecologically, Subdoligranulum sp. serves as a model organism for studying the interplay between diet, microbiome composition, and host health. Its ability to produce butyrate underscores the significance of microbial metabolites in enhancing the gut barrier function and modulating immune responses, illustrating the complex interdependence between gut microbiota and host homeostasis. This highlights the potential of targeting butyrate-producing bacteria through dietary interventions or probiotics to promote gut health and prevent gastrointestinal diseases. |
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