| Description | Flavonifractor hominis is a Gram-positive, rod-shaped bacterium found predominantly in the human gut, exhibiting anaerobic metabolic characteristics. This microbe thrives in oxygen-deprived environments, making it an integral component of the gut microbiome. F. hominis demonstrates a unique ability to utilize starch, which it metabolizes into various beneficial compounds, enhancing its ecological niche within the digestive system. One of the primary metabolic byproducts of F. hominis is glutamate, an amino acid vital for numerous cellular functions and neurotransmission. Additionally, this bacterium produces riboflavin (vitamin B2), which plays a crucial role in energy metabolism and the maintenance of healthy skin and eyes. Butyrate, another significant short-chain fatty acid generated by F. hominis, contributes to gut health by promoting colonic cell function and serving as an energy source for intestinal epithelial cells. The synthesis of folate, a critical B vitamin for DNA synthesis and repair, further underscores the bacterium’s importance in maintaining human health. Moreover, F. hominis is recognized for its role in the overall balance of the gut microbiota, which is essential for optimal digestive health and immune function. Its presence can impact various physiological processes, and disturbances in its levels may be associated with gut dysbiosis. Research is ongoing to fully elucidate the implications of F. hominis in both health and disease, particularly its potential contributions to metabolic disorders and inflammation. Understanding its capabilities and interactions within the gut ecosystem may pave the way for therapeutic applications, especially in restoring gut microbiota harmony. |
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