| Description | Lachnospira intestinalis is a Gram-positive, rod-shaped bacterium that thrives in the anaerobic environment of the human gut. This microbe is a member of the Firmicutes phylum and plays a significant role in the gastrointestinal ecosystem. Its metabolism primarily involves the fermentation of starch, leading to the production of essential short-chain fatty acids such as acetate and propionate, alongside folate, which is vital for various bodily functions. The ability of Lachnospira intestinalis to metabolize complex carbohydrates like starch underscores its importance in dietary fiber breakdown, contributing to gut health by helping to maintain a balanced microbiota. As it ferments starch, it generates short-chain fatty acids, which serve as energy sources for colon cells and have been associated with various health benefits, including anti-inflammatory effects and regulation of gut motility. In addition to its metabolic capabilities, Lachnospira intestinalis is noteworthy for its relationship with human health. Research has indicated that alterations in its abundance may correlate with various gastrointestinal disorders, including inflammatory bowel disease (IBD) and obesity. This underscores its potential role as a biomarker for gut health and disease states. Furthermore, as a component of the gut microbiome, it may influence immune response and modulate inflammation, forming a crucial link between diet, microbial metabolism, and overall health. Its presence in the gut microbiome highlights the intricate interactions between microbes and their human hosts, emphasizing the importance of maintaining a healthy microbial balance for optimal health. |
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